Improved intratumoral penetration of IL12 immunocytokine enhances the antitumor efficacy
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DOI: 10.3389/fimmu.2022.1034774
Abstract: Tumor-targeting antibody (Ab)-fused cytokines, referred to as immunocytokines, are designed to increase antitumor efficacy and reduce toxicity through the tumor-directed delivery of cytokines. However, the poor localization and intratumoral penetration of immunocytokines, especially in solid… read more here.
Keywords: antitumor; mil12; hct; intratumoral penetration ... See more keywords