Simulated Intravenous versus Inhaled Tobramycin with or without Intravenous Ceftazidime Evaluated against Hypermutable Pseudomonas aeruginosa via a Dynamic Biofilm Model and Mechanism-Based Modeling
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DOI: 10.1128/aac.02203-21
Abstract: Acute exacerbations of chronic respiratory infections in patients with cystic fibrosis are highly challenging due to hypermutable Pseudomonas aeruginosa biofilm formation and resistance emergence. We aimed to systematically evaluate the effects of intravenous versus inhaled… read more here.
Keywords: intravenous ceftazidime; ceftazidime; combination; biofilm ... See more keywords