Why Collecting Pharmacokinetic Information After Intravenous Drug Administration Is Important
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.763
Abstract: A new drug application (NDA) for a systemically active, new therapeutic entity (NTE) may contain clinical studies that administered a small molecule or a biologic only by the intended route. This may be self-evident for… read more here.
Keywords: administration; information; drug administration; drug ... See more keywords
Pelvic and acetabular fracture management in intravenous drug users
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Orthopaedic and Trauma Surgery"
DOI: 10.1007/s00402-020-03499-z
Abstract: Introduction Pelvic and acetabular fractures are significant injuries associated with high morbidity or mortality. Intravenous drug users (IVDU) represent a challenging group of patients, with an increased risk of complications and infection. To our knowledge… read more here.
Keywords: pelvic acetabular; acetabular fracture; fracture; drug users ... See more keywords
Reply: Intravenous Drug Use-Associated Endocarditis Complicating Research of Antibiotic Prophylaxis and Guideline Recommendations.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2019.01.001
Abstract: Dr. Eddinger has focused on an important contemporary aspect of the epidemiology of infective endocarditis (IE), which has become a marker of the ongoing opioid epidemic in the United States. As evidenced in Dr. Eddinger’s… read more here.
Keywords: reply intravenous; use associated; drug use; endocarditis ... See more keywords
Hepatitis C treatment outcome in former or current intravenous drug users coinfected with HIV, with or without directly observed therapy
Sign Up to like & getrecommendations! Published in 2020 at "Infectious Diseases"
DOI: 10.1080/23744235.2020.1806352
Abstract: Abstract Background Intravenous drug users (IDUs) with hepatitis C virus (HCV)/human immunodeficiency virus (HIV)-coinfection are recognised as a high-risk, vulnerable group. Methods Between February 2015 and April 2018, a single-centre, non-interventional cohort study was conducted… read more here.
Keywords: drug users; treatment; hiv; therapy ... See more keywords
Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users
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DOI: 10.1093/ofid/ofx102
Abstract: Abstract Sixty-one percent of intravenous drug users (IVDUs) who received outpatient parenteral antibiotic therapy (OPAT) failed treatment. Hospital readmission and adverse drug reactions occurred in 25%. By multivariate analysis, time since last IVDU was associated… read more here.
Keywords: outpatient parenteral; drug users; antibiotic therapy; drug ... See more keywords
Accumulation of foamy macrophages in the bone marrow following chronic intravenous drug use
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Haematology"
DOI: 10.1111/bjh.18435
Abstract: A 37yearold man with a longstanding history of intravenous drug abuse presented with a pathological fracture of the right hip and isolated anaemia (haemoglobin concentration 88 g/l). Magnetic resonance imaging of the hip showed multifocal… read more here.
Keywords: foamy macrophages; bone marrow; bone; accumulation foamy ... See more keywords
Pregnant intravenous drug user tricuspid valve infective endocarditis treated with a successful simultaneous valve replacement and Cesarean section
Sign Up to like & getrecommendations! Published in 2018 at "Echocardiography"
DOI: 10.1111/echo.14122
Abstract: A 30‐year‐old female patient known to be an intravenous drug user (IVDU) was admitted to Bajcsy‐Zsilinszky Hospital Cardiology Intensive Care Unit at 29‐week gestation with severe sepsis and right heart failure. She had methicillin‐sensitive Staphylococcus… read more here.
Keywords: drug user; infective endocarditis; valve infective; intravenous drug ... See more keywords
Evolutionary characteristics and immune mutation of hepatitis C virus genotype 1b among intravenous drug users in mainland, China
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13647
Abstract: China is one of the countries with the heaviest burden of hepatitis C virus (HCV) worldwide, especially subtype 1b. To better control hepatitis C, insights into the characteristics of dynamic spread and genomic mutations are… read more here.
Keywords: among intravenous; hepatitis virus; hepatitis; china ... See more keywords
Infective endocarditis in an intravenous drug user: multiple fatal complications
Sign Up to like & getrecommendations! Published in 2021 at "BMJ Case Reports"
DOI: 10.1136/bcr-2020-239376
Abstract: Here, we present a case of a 43-year-old patient with a background of active intravenous drug use who was diagnosed with aortic valve endocarditis. This was complicated by extensive acute embolic stroke and acute splenic,… read more here.
Keywords: drug user; infective endocarditis; drug; endocarditis intravenous ... See more keywords
P440 Assessment of potential pre-exposure prophylaxis (prep) compliance in intravenous drug users accessing outreach services
Sign Up to like & getrecommendations! Published in 2019 at "Sexually Transmitted Infections"
DOI: 10.1136/sextrans-2019-sti.525
Abstract: Background Internationally, approximately one out of every ten new HIV infections has previously been attributed to intravenous drug use (IVDU). PrEP compliance among people with intravenous drug use (PWID) may decrease new HIV infection. This… read more here.
Keywords: intravenous drug; risk; prep; prep compliance ... See more keywords
Surgical treatment of infective endocarditis in intravenous drug abusers
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cardiothoracic Surgery"
DOI: 10.1186/s13019-021-01491-1
Abstract: Background Despite current progress in antibiotic therapy and medical management, infective endocarditis remains a serious condition presenting with high mortality rates. It also is a life-threatening complication in patients with a history of chronic intravenous… read more here.
Keywords: intravenous drug; treatment infective; infective endocarditis; endocarditis ... See more keywords