Overcoming the Challenges of Low Drug Solubility in the Intravenous Formulation of Solithromycin.
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DOI: 10.1016/j.xphs.2017.10.030
Abstract: Solithromycin is a fluoro-ketolide (a fourth-generation macrolide) antibiotic that has been undergoing clinical trials for the treatment of community-acquired bacterial pneumonia. In this study, development of the tri-amino acid-buffered solithromycin intravenous (IV) formulation was performed… read more here.
Keywords: buffered formulation; solithromycin; formulation; overcoming challenges ... See more keywords
Safety of an Intravenous Formulation of Voriconazole as an Intramuscular Injection in Pigeons (Columba livia f. domestica)
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DOI: 10.1647/20-00006
Abstract: Abstract: Aspergillosis is a common disease in birds. Currently, avian aspergillosis is treated with voriconazole administered orally, although intramuscular (IM) administration increases bioavailability and is more effective in treating generalized aspergillosis. The objective of this… read more here.
Keywords: injection; intravenous formulation; formulation; safety intravenous ... See more keywords