Intravenous infusion for the controlled exposure to the dual ABCB1 and ABCG2 inhibitor elacridar in nonhuman primates
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DOI: 10.1007/s13346-017-0472-6
Abstract: Elacridar (GF120918) is a highly potent inhibitor of both P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2), the main efflux transporters expressed at the blood-brain barrier (BBB). Elacridar shows very low aqueous solubility, which complicates… read more here.
Keywords: controlled exposure; elacridar; infusion; intravenous infusion ... See more keywords
Preservation of interhemispheric cortical connections through corpus callosum following intravenous infusion of mesenchymal stem cells in a rat model of cerebral infarction
Sign Up to like & getrecommendations! Published in 2018 at "Brain Research"
DOI: 10.1016/j.brainres.2018.05.033
Abstract: Systemic administration of mesenchymal stem cells (MSCs) following cerebral infarction exerts functional improvements. Previous research has suggested potential therapeutic mechanisms that promote neuroprotection and synaptogenesis. These include secretion of neurotrophic factors, remodeling of neural circuits,… read more here.
Keywords: corpus callosum; preservation; callosum; intravenous infusion ... See more keywords
In situ degradation of antibiotic residues in medical intravenous infusion bottles using high energy electron beam irradiation
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep39928
Abstract: This study reported an immediate approach for the degradation of three antibiotic (amoxicillin, ofloxacin, and cefradine) residues in medical intravenous infusion bottles (MIIBs) using high energy electron beam (HEEB) irradiation. The effects of irradiation doses,… read more here.
Keywords: degradation; irradiation; infusion bottles; medical intravenous ... See more keywords
Defining the right diluent for intravenous infusion of therapeutic antibodies
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DOI: 10.1080/19420862.2019.1685814
Abstract: ABSTRACT Therapeutic monoclonal antibodies (mAbs) are commonly administered to patients through intravenous (IV) infusion, which involves diluting the medication into an infusion solution (e.g., saline and 5% dextrose). Using the wrong diluent can cause product… read more here.
Keywords: diluent intravenous; right diluent; infusion; infusion therapeutic ... See more keywords
Intravenous infusion of glucose improved farrowing performance of hyperprolific crossbred sows.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of animal science"
DOI: 10.1093/jas/skab061
Abstract: The sow at parturition is challenged with respect to energy status due to increases in energetic expenses associated with 1) nest building 2) uterine contractions and 3) colostrum production. A previous study indicated that sows… read more here.
Keywords: infusion; birth; intravenous infusion; blood ... See more keywords
Intravenous Infusion of Mesenchymal Stem Cells Promotes the Survival of Random Pattern Flaps in Rats
Sign Up to like & getrecommendations! Published in 2021 at "Plastic and Reconstructive Surgery"
DOI: 10.1097/prs.0000000000008327
Abstract: Background: Surgical reconstruction options of soft-tissue defects often include random pattern skin flaps. Flap survival depends on flap size and rotation arc and can be challenging regarding flap perfusion, leading to wound healing complications, insufficient… read more here.
Keywords: intravenous infusion; mesenchymal stem; stem cells; stem ... See more keywords
Continuous intravenous infusion of enoxaparin controls thrombin formation more than standard subcutaneous administration in critically ill patients. A sub‐study of the ENOKSI thromboprophylaxis RCT
Sign Up to like & getrecommendations! Published in 2020 at "Acta Anaesthesiologica Scandinavica"
DOI: 10.1111/aas.13697
Abstract: Standard subcutaneous low‐molecular‐weight heparin (LMWH) thromboprophylaxis yields low anti‐factor Xa activity in patients in the intensive care unit (ICU). The aim of the study was to assess coagulation status in ICU patients randomized to receive… read more here.
Keywords: standard subcutaneous; study; enoxaparin; intravenous infusion ... See more keywords
Arsenic trioxide intravenous infusion combined with transcatheter arterial chemoembolization for the treatment of hepatocellular carcinoma with pulmonary metastasis: Long‐term outcome analysis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.13529
Abstract: To evaluate the safety, clinical efficacy, and long‐term outcome of arsenic trioxide (As2O3) intravenous infusion for pulmonary metastases in patients with HCC. read more here.
Keywords: long term; term outcome; intravenous infusion; arsenic trioxide ... See more keywords
IL15 by Continuous Intravenous Infusion to Adult Patients with Solid Tumors in a Phase I Trial Induced Dramatic NK-Cell Subset Expansion
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DOI: 10.1158/1078-0432.ccr-18-3468
Abstract: Purpose: The first-in-human clinical trial with human bolus intravenous infusion IL15 (rhIL15) was limited by treatment-associated toxicity. Here, we report toxicity, immunomodulation, and clinical activity of rhIL15 administered as a 10-day continuous intravenous infusion (CIV)… read more here.
Keywords: infusion; phase trial; intravenous infusion; day ... See more keywords
Treatment of Pegylated Asparaginase-Induced Hypertriglyceridemia with Continuous Intravenous Infusion of Insulin and Heparin: A Case Report
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DOI: 10.1159/000505773
Abstract: Background: Pegylated asparaginase may induce prolonged hypertriglyceridemia. To date, there is no standard management of this complication. Here, we present a case report of pegylated asparaginase-induced hypertriglyceridemia and hepatotoxicity successfully treated with continuous intravenous infusion… read more here.
Keywords: insulin heparin; intravenous infusion; pegylated asparaginase; infusion insulin ... See more keywords
The in-use stability of the rituximab biosimilar Rixathon®/Riximyo® upon preparation for intravenous infusion
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Oncology Pharmacy Practice"
DOI: 10.1177/1078155217731506
Abstract: Purpose The purpose of this study was to evaluate the in-use physicochemical and biological stability of the Sandoz rituximab biosimilar, marketed under the trade names Rixathon® and Riximyo® in the European Union, upon preparation for… read more here.
Keywords: infusion; rixathon riximyo; rituximab biosimilar; intravenous infusion ... See more keywords