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Published in 2020 at "Brain and Behavior"
DOI: 10.1002/brb3.1875
Abstract: Postoperative cognitive dysfunction is a debilitating postoperative complication. The perioperative neuroprotective effect of lidocaine has conflicting results. read more here.
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Published in 2021 at "European journal of clinical pharmacology"
DOI: 10.1007/s00228-021-03219-5
Abstract: PURPOSE Although different forms of lidocaine are used for migraine attack headaches, the effect of intravenous lidocaine is still limited. This study aimed to investigate the effects of intravenous lidocaine infusion for the treatment of… read more here.
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Published in 2018 at "Techniques in Coloproctology"
DOI: 10.1007/s10151-018-1890-2
Abstract: Selection criteria We included randomized controlled trials comparing the effect of continuous perioperative IV lidocaine infusion either with placebo, or no treatment, or with thoracic epidural analgesia (TEA) in adults undergoing elective or urgent surgery… read more here.
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Published in 2017 at "Journal of Clinical Monitoring and Computing"
DOI: 10.1007/s10877-017-0035-x
Abstract: Intraoperative lidocaine infusion has become widely accepted as an adjunct to general anesthesia where its use has been associated with opioid-sparing and enhanced recovery. The aims of this study were to determine whether or not… read more here.
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Published in 2018 at "American Journal of Emergency Medicine"
DOI: 10.1016/j.ajem.2017.12.027
Abstract: Introduction: This study was designed to assess the possible superiority of intravenous lidocaine to morphine for pain management. Methods: This was a randomized double blind controlled superiority trial, carried on in the emergency department (ED).… read more here.
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Published in 2020 at "British journal of anaesthesia"
DOI: 10.1016/j.bja.2020.03.034
Abstract: BACKGROUND Intravenous lidocaine has been shown to reduce opioid consumption and is associated with favourable outcomes after surgery. In this study, we explored whether intraoperative lidocaine reduces intraoperative opioid use and length of stay (LOS)… read more here.
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Published in 2021 at "Gastrointestinal endoscopy"
DOI: 10.1016/j.gie.2021.01.008
Abstract: BACKGROUND AND AIMS Some studies have shown that intravenous (IV) lidocaine reduces the dose requirement of propofol in gastrointestinal (GI) endoscopic procedures. We conducted this study to evaluate the efficacy and safety of the combination… read more here.
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Published in 2018 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2017.1404016
Abstract: We read with great interest the paper titled ‘Bolus administration of intravenous lidocaine reduces pain after an elective caesarean section: Findings from a randomised, double-blind, placebo-controlled trial’ by Gholipour Baradari et al. (2017) that was… read more here.
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Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000023332
Abstract: Abstract Background: Perioperative intravenous lidocaine has been reported to have analgesic and opioid-sparing effects in many kinds of surgery. Several studies have evaluated its use in the settings of spine surgery. The aim of the… read more here.
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Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000030476
Abstract: Background: This study aimed at providing an updated evidence of the association between intraoperative lidocaine and risk of postcardiac surgery cognitive deficit. Methods: Randomized clinical trials (RCTs) investigating effects of intravenous lidocaine against cognitive deficit… read more here.
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Published in 2020 at "Anaesthesia"
DOI: 10.1111/anae.15270
Abstract: Intravenous lidocaine is used widely for its effect on postoperative pain and recovery but it can be, and has been, fatal when used inappropriately and incorrectly. The risk‐benefit ratio of i.v. lidocaine varies with type… read more here.