Intravenous vs oral acetaminophen in sinus surgery: A randomized clinical trial
Sign Up to like & getrecommendations! Published in 2020 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.375
Abstract: Multimodal perioperative analgesia including acetaminophen is recommended by current guidelines. The comparative efficacy of intravenous vs oral acetaminophen in sinus surgery is unknown. We aimed to determine whether intravenous or oral acetaminophen results in superior… read more here.
Keywords: acetaminophen; intravenous oral; oral acetaminophen; sinus surgery ... See more keywords
Population pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing regimens.
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DOI: 10.1007/s00228-021-03174-1
Abstract: PURPOSE This study aimed to characterize pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing scheme. METHODS Children treated with ciprofloxacin were included. Pharmacokinetics were described using non-linear mixed-effect modelling and validated with… read more here.
Keywords: intravenous oral; children optimize; pharmacokinetics intravenous; ciprofloxacin ... See more keywords
Nicotine Population Pharmacokinetics in Healthy Smokers After Intravenous, Oral, Buccal and Transdermal Administration
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DOI: 10.1007/s40262-020-00960-5
Abstract: Background In 4 decades, numerous nicotine replacement therapy products have been developed. Population pharmacokinetic models can support exposure–response modeling and inform nicotine replacement therapy product development, but only limited model-based cross-study population pharmacokinetic analyses for… read more here.
Keywords: replacement therapy; population; intravenous oral; nicotine replacement ... See more keywords
Single intravenous and oral pharmacokinetics of danofloxacin in the goat
Sign Up to like & getrecommendations! Published in 2021 at "Small Ruminant Research"
DOI: 10.1016/j.smallrumres.2021.106393
Abstract: Abstract Respiratory diseases including pneumonia are a common concern in goats, with M. Haemolytica the usual causative organism. Owing to danofloxacin’s wide spectrum of activity, it is used to treat such disease in goats. The… read more here.
Keywords: administration; intravenous oral; single intravenous; danofloxacin ... See more keywords
Oral bioavailability and pharmacokinetics of esculetin following intravenous and oral administration in rats
Sign Up to like & getrecommendations! Published in 2021 at "Xenobiotica"
DOI: 10.1080/00498254.2021.1925774
Abstract: Abstract Esculetin is the main active ingredient isolated from Artemisia montana (Nakai) Pamp. and Euphorbia lathyris L. The present study investigated the oral bioavailability and pharmacokinetics of esculetin in rats, following intravenous and oral administration.… read more here.
Keywords: oral bioavailability; bioavailability pharmacokinetics; intravenous oral; esculetin ... See more keywords
Pharmacokinetics of Afatinib after Intravenous and Oral Administrations in Rats Using Validated UPLC MS/MS Assay.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmac110
Abstract: Afatinib is designated as the first-line management therapy for patients with advanced non-small cell lung cancer, and metastatic head and neck cancer. LC coupled to MS/MS can be utilised in therapeutic drug monitoring to ensure… read more here.
Keywords: pharmacokinetics afatinib; administrations rats; intravenous oral; oral administrations ... See more keywords
Impact and barriers of a pharmacist‐led practice with computerized reminders on intravenous to oral antibiotic conversion for community‐acquired pneumonia inpatients
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13397
Abstract: Intravenous to oral (IV‐PO) antibiotic conversion, one of the critical elements in antimicrobial stewardship (AMS), is not well implemented in China. Studies on the strategy to apply the IV‐PO conversion are needed. Our objective was… read more here.
Keywords: impact barriers; intravenous oral; antibiotic conversion; conversion ... See more keywords
Pharmacokinetics of an intravenous and oral dose of enrofloxacin in white rhinoceros (Ceratotherium simum)
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DOI: 10.1111/jvp.12747
Abstract: South Africa currently loses over 1000 white rhinoceros (Ceratotherium simum) each year to poaching incidents, and numbers of severely injured victims found alive have increased dramatically. However, little is known about the antimicrobial treatment of… read more here.
Keywords: administration; intravenous oral; ceratotherium simum; white rhinoceros ... See more keywords
Pharmacokinetics of neomycin sulfate after intravenous and oral administrations in swine.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of veterinary pharmacology and therapeutics"
DOI: 10.1111/jvp.12981
Abstract: The aminoglycoside antibiotic neomycin, which is used to treat external or internal bacterial infections, is primarily administered in veterinary medicine as a sulfate salt. However, no information is available on the pharmacokinetic characteristics and absolute… read more here.
Keywords: intravenous oral; administrations swine; sulfate intravenous; oral administrations ... See more keywords
Model Based Estimation of Posaconazole Tablet and Suspension Bioavailability in Hospitalized Children Using Real-World Therapeutic Drug Monitoring Data in Patients Receiving Intravenous and Oral Dosing
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DOI: 10.1128/aac.00077-23
Abstract: Invasive fungal infections are a major cause of morbidity and mortality for immunocompromised patients. Posaconazole is approved for treatment and prophylaxis of invasive fungal infection in adult patients, with intravenous, oral suspension, and gastroresistant/delayed-released tablet… read more here.
Keywords: suspension bioavailability; intravenous oral; tablet; model ... See more keywords
16 Poor availability of age-appropriate drug formulations in DR Congo: a barrier to switch from intravenous to oral antibiotics in children admitted to Kisantu hospital
Sign Up to like & getrecommendations! Published in 2023 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2023-esdppp.16
Abstract: In children with severe bacterial infection in low-resource settings, switch from intravenous to oral antibiotics is important to reduce nosocomial infections and costs. We report barriers to reliable oral antibiotic administration in children under five… read more here.
Keywords: switch; admitted kisantu; intravenous oral; age ... See more keywords