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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1425-9_15
Abstract: The complex bone marrow microenvironment or niche is an important anatomical structure responsible for hematopoiesis and providing support to the immune cells function. Being the source of immune and blood cells, the interaction of these…
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Keywords:
bone;
marrow microenvironment;
intravital imaging;
bone marrow ... See more keywords
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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1425-9_16
Abstract: Haematopoietic stem cells (HSCs) are instrumental in driving the generation of mature blood cells, essential for various functions including immune defense and tissue remodeling. They reside within a specialised bone marrow (BM) microenvironment , or…
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Keywords:
marrow niches;
intravital imaging;
imaging bone;
bone ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7762-8_13
Abstract: The liver is a vital organ in the body. It has various essential functions, including detoxification, protein synthesis, and control of infection. Because of its medical importance, liver diseases such as hepatitis and cirrhosis can…
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Keywords:
cell dynamics;
intravital imaging;
liver cell;
liver ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7762-8_2
Abstract: The bone marrow is a unique microenvironment where blood cells are produced and released into the circulation. At the top of the blood cell lineage are the hematopoietic stem cells (HSC), which are thought to…
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Keywords:
hemodynamics;
permeability;
intravital imaging;
bone marrow ... See more keywords
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Published in 2020 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2020.102958
Abstract: Nanomedicine has proven promising in preclinical studies. However, only few formulations have been successfully translated to clinical use. A thorough understanding of how nanoparticles interact with cells in vivo is essential to accelerate the clinical…
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Keywords:
intravital imaging;
vivo;
nanoparticle delivery;
delivery vivo ... See more keywords
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Published in 2019 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2019.112972
Abstract: Abstract Intravital imaging of the immune system is a powerful technique for studying biology of the immune response in the spinal cord using a variety of disease models ranging from traumatic injury to autoimmune disorders.…
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Keywords:
intravital imaging;
imaging immune;
cells interactions;
immune cells ... See more keywords
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Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c04238
Abstract: NAD(P)H is a vital hydrogen donor and electron carrier involved in numerous biological processes. The development of small-molecule tools for intravital imaging of NAD(P)H is significant for further exploring their pathophysiological roles. Herein, we rationally…
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Keywords:
red emitting;
imaging nad;
mitochondria nucleus;
intravital imaging ... See more keywords
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Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-01538-9
Abstract: The bone marrow is a central organ of the immune system, which hosts complex interactions of bone and immune compartments critical for hematopoiesis, immunological memory, and bone regeneration. Although these processes take place over months,…
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Keywords:
intravital imaging;
longitudinal intravital;
bone;
plasticity ... See more keywords
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Published in 2021 at "Communications biology"
DOI: 10.1038/s42003-021-02757-z
Abstract: Aging or injury in Drosophila intestine promotes intestinal stem cell (ISC) proliferation and enteroblast (EB) differentiation. However, the manner the local physiology couples with dynamic EB differentiation assessed by traditional lineage tracing method is still…
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Keywords:
drosophila;
flyvab;
intravital imaging;
imaging strategy ... See more keywords
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Published in 2023 at "Journal of Cell Science"
DOI: 10.1242/jcs.260285
Abstract: ABSTRACT Wnt signalling has been implicated as a driver of tumour cell metastasis, but less is known about which branches of Wnt signalling are involved and when they act in the metastatic cascade. Here, using…
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Keywords:
cell;
tumour cell;
wnt;
invasion ... See more keywords
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Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.620471
Abstract: Intravital microscopy (IVM) is a unique imaging method providing insights in cellular functions and interactions in real-time, without the need for tissue extraction from the body. IVM of the lungs has specific challenges such as…
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Keywords:
pulmonary immune;
intravital imaging;
inflammation;
inflammation infection ... See more keywords