Measurement of Endothelial Barrier Function in Mouse Models of Cerebral Cavernous Malformations Using Intravital Microscopy.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0640-7_28
Abstract: Vascular permeability is a major function of the microvasculature that is regulated by multiple factors including blood pressure, blood viscosity, and endothelial barrier function. Intravital microscopy has been used to directly assess vascular permeability in… read more here.
Keywords: microscopy; intravital microscopy; endothelial barrier; barrier function ... See more keywords
Intravital Microscopy in Atherosclerosis Research.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1924-7_40
Abstract: Atherosclerosis is a lipid-driven inflammatory disorder that narrows the arterial lumen and can induce life-threatening complications from coronary artery disease, cerebrovascular disease, and peripheral artery disease. On a mechanistic level, the development of novel cellular-resolution… read more here.
Keywords: intravital microscopy; atherosclerosis research; microscopy; atherosclerosis ... See more keywords
Imaging Glioma Progression by Intravital Microscopy.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8769-6_16
Abstract: We describe here a method for generating mouse orthotopic gliomas in order to follow their progression over time by multi-photon laser scanning microscopy. After craniotomy of the parietal bone, glioma cells are implanted in the… read more here.
Keywords: microscopy; intravital microscopy; progression intravital; glioma progression ... See more keywords
Analysis of the Effect of IL-1β on Blood—Brain Barrier Permeability in M6 Glioma Mouse Model Using Intravital Microscopy
Sign Up to like & getrecommendations! Published in 2019 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-019-04661-3
Abstract: We studied the effect of IL-1β on the permeability of brain capillaries in healthy mice. Intravital microscopy demonstrated that parenteral administration of IL-1β was followed by an increase in vascular permeability ensuring passage of free… read more here.
Keywords: blood brain; microscopy; intravital microscopy; permeability ... See more keywords
Imaging the pharmacology of nanomaterials by intravital microscopy: Toward understanding their biological behavior.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2016.05.023
Abstract: Therapeutic nanoparticles (NPs) can deliver cytotoxic chemotherapeutics and other drugs more safely and efficiently to patients; furthermore, selective delivery to target tissues can theoretically be accomplished actively through coating NPs with molecular ligands, and passively… read more here.
Keywords: nanomaterials intravital; microscopy; intravital microscopy; pharmacology ... See more keywords
Imaging the neutrophil: Intravital microscopy provides a dynamic view of neutrophil functions in host immunity.
Sign Up to like & getrecommendations! Published in 2019 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2019.01.003
Abstract: Neutrophils are the first cellular responders of the immune system. They employ their impressive arsenal of microbicidal molecules to provide rapid and efficient defense against pathogens. However, the role of neutrophils extends far beyond microbial… read more here.
Keywords: neutrophil intravital; microscopy; microscopy provides; intravital microscopy ... See more keywords
A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo
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DOI: 10.1038/s41598-019-44777-0
Abstract: The pancreatic islet is a complex micro-organ containing numerous cell types, including endocrine, immune, and endothelial cells. The communication of these systems is lost upon isolation of the islets, and therefore the pathogenesis of diabetes… read more here.
Keywords: microscopy; vivo; intravital microscopy; platform ... See more keywords
New frontiers in intravital microscopy of the kidney
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Nephrology and Hypertension"
DOI: 10.1097/mnh.0000000000000313
Abstract: Purpose of review Intravital imaging with multiphoton microscopy enables the detailed study of dynamic cellular processes within functioning organs in living animals, in ways that would not otherwise be possible. It therefore represents a powerful… read more here.
Keywords: microscopy; microscopy kidney; new frontiers; intravital microscopy ... See more keywords
Fluorescent labeling of endogenous platelets for intravital microscopy: Effects on platelet function
Sign Up to like & getrecommendations! Published in 2018 at "Microcirculation"
DOI: 10.1111/micc.12457
Abstract: Monitoring endogenous platelets during intravital microscopy often involves two approaches: fluorescently labeled antibodies or genetic models of platelet‐specific fluorescent protein expression. Due to limited data available on platelet functional changes induced by these methods, we… read more here.
Keywords: microscopy; intravital microscopy; endogenous platelets; fluorescent labeling ... See more keywords
In Vivo flow Cytometry Combined with Intravital Microscopy to Monitor Synchronous Kinetics of Transplanted BM-MNCs in Peripheral Blood and Bone Marrow
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-114379
Abstract: Limited sources and finite numbers of hematopoietic stem cells (HSCs) have always been difficult problems to overcome in clinical HSC transplantation (HSCT). Improving the bone marrow (BM) homing efficiency of HSC has become an intensely… read more here.
Keywords: microscopy; intravital microscopy; transplanted mncs; flow cytometry ... See more keywords
A new analysis approach for single nephron GFR in intravital microscopy of mice
Sign Up to like & getrecommendations! Published in 2020 at "F1000Research"
DOI: 10.12688/f1000research.26888.3
Abstract: Background: Intravital microscopy is an emerging technique in life science with applications in kidney research. Longitudinal observation of (patho-)physiological processes in living mice is possible in the smallest functional unit of the kidney, a single… read more here.
Keywords: single nephron; microscopy; analysis; intravital microscopy ... See more keywords