Electrophysiological effects of nicotinic and electrical stimulation of intrinsic cardiac ganglia in the absence of extrinsic autonomic nerves in the rabbit heart
Sign Up to like & getrecommendations! Published in 2018 at "Heart Rhythm"
DOI: 10.1016/j.hrthm.2018.05.018
Abstract: Background The intrinsic cardiac nervous system is a rich network of cardiac nerves that converge to form distinct ganglia and extend across the heart and is capable of influencing cardiac function. Objective The goals of… read more here.
Keywords: intrinsic cardiac; rabbit heart; stimulation; electrical stimulation ... See more keywords
Early structural alterations of intrinsic cardiac ganglionated plexus in spontaneously hypertensive rats.
Sign Up to like & getrecommendations! Published in 2022 at "Histology and histopathology"
DOI: 10.14670/hh-18-453
Abstract: Persistent arterial hypertension leads to structural and functional remodeling of the heart resulting in myocardial ischemia, fibrosis, hypertrophy, and eventually heart failure. Previous studies have shown that individual neurons composing the intracardiac ganglia are hypertrophied… read more here.
Keywords: ganglionated plexus; intrinsic cardiac; microscopy; structural alterations ... See more keywords
Atrial Innervation Patterns of Intrinsic Cardiac Autonomic Nerves
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Korean Medical Science"
DOI: 10.3346/jkms.2018.33.e253
Abstract: Background Although ganglionated plexi (GPs) are important in the pathogenesis of arrhythmia, their patterns of atrial innervation have remained unclear. We investigated patterns of GP innervation to cardiac atria and the neuroanatomical interconnections among GPs… read more here.
Keywords: experiment ctb; intrinsic cardiac; gps; innervation ... See more keywords
Recording plasticity in neuronal activity in the rodent intrinsic cardiac nervous system using calcium imaging techniques
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Synaptic Neuroscience"
DOI: 10.3389/fnsyn.2023.1104736
Abstract: The intrinsic cardiac nervous system (ICNS) is composed of interconnected clusters of neurons called ganglionated plexi (GP) which play a major role in controlling heart rate and rhythm. The function of these neurons is particularly… read more here.
Keywords: calcium; intrinsic cardiac; plasticity; activity ... See more keywords
Isogenic Human-Induced Pluripotent Stem-Cell-Derived Cardiomyocytes Reveal Activation of Wnt Signaling Pathways Underlying Intrinsic Cardiac Abnormalities in Rett Syndrome
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232415609
Abstract: Rett syndrome (RTT) is a severe neurodevelopmental disorder caused by MeCP2 mutations. Nonetheless, the pathophysiological roles of MeCP2 mutations in the etiology of intrinsic cardiac abnormality and sudden death remain unclear. In this study, we… read more here.
Keywords: pluripotent stem; rett syndrome; intrinsic cardiac; ipsc cms ... See more keywords
Intrinsic Cardiac Neuromodulation in the Management of Atrial Fibrillation- A Potential Missing Link?
Sign Up to like & getrecommendations! Published in 2023 at "Life"
DOI: 10.3390/life13020383
Abstract: Atrial fibrillation (AF) is the most common supraventricular arrhythmia that is linked with higher cardiovascular morbidity and mortality. Recent evidence has demonstrated that catheter-based pulmonary vein isolation (PVI) is not only a viable alternative but… read more here.
Keywords: neuromodulation management; intrinsic cardiac; neuromodulation; cardiac neuromodulation ... See more keywords