M2 macrophage-derived exosomes suppress tumor intrinsic immunogenicity to confer immunotherapy resistance
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DOI: 10.1080/2162402x.2023.2210959
Abstract: ABSTRACT T-cell-based immune checkpoint blockade therapy (ICB) can be undermined by local immunosuppressive M2-like tumor-associated macrophages (TAMs). However, modulating macrophages has proved difficult as the molecular and functional features of M2-TAMs on tumor growth are… read more here.
Keywords: macrophage derived; resistance; tumor intrinsic; intrinsic immunogenicity ... See more keywords