Articles with "intrinsic phenotypic" as a keyword



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Tumor cell-intrinsic phenotypic plasticity facilitates adaptive cellular reprogramming driving acquired drug resistance

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Published in 2017 at "Journal of Cell Communication and Signaling"

DOI: 10.1007/s12079-017-0435-1

Abstract: The enthusiasm about successful novel therapeutic strategies in cancer is often quickly dampened by the development of drug resistance. This is true for targeted therapies using tyrosine kinase inhibitors for EGFR or BRAF mutant cancers,… read more here.

Keywords: drug resistance; intrinsic phenotypic; drug; resistance ... See more keywords