Articles with "intrinsic subtypes" as a keyword



Correlations Between Ultrasonographic Findings of Invasive Lobular Carcinoma of the Breast and Intrinsic Subtypes.

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Published in 2018 at "Ultraschall in der Medizin"

DOI: 10.1055/a-0715-1668

Abstract: PURPOSE  To analyze the ultrasonographic findings of invasive lobular carcinoma (ILC) of the breast in 360 women and the correlations between the characteristics and the intrinsic subtypes. MATERIALS AND METHODS  We evaluated the imaging findings… read more here.

Keywords: findings invasive; invasive lobular; lobular carcinoma; ultrasonographic findings ... See more keywords

Intrinsic subtypes and benefit from postmastectomy radiotherapy in node-positive premenopausal breast cancer patients who received adjuvant chemotherapy – results from two independent randomized trials

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Published in 2018 at "Acta Oncologica"

DOI: 10.1080/0284186x.2017.1401735

Abstract: Abstract Background: The study of the intrinsic molecular subtypes of breast cancer has revealed differences among them in terms of prognosis and response to chemotherapy and endocrine therapy. However, the ability of intrinsic subtypes to… read more here.

Keywords: chemotherapy; breast; radiotherapy; breast cancer ... See more keywords

Multi-tissue transcriptome-wide association studies identified 235 genes for intrinsic subtypes of breast cancer.

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Published in 2024 at "Journal of the National Cancer Institute"

DOI: 10.1093/jnci/djae041

Abstract: BACKGROUND Although genome-wide association studies (GWAS) of breast cancer (BC) identified common variants which differ between intrinsic subtypes, genes through which these variants act to impact BC risk have not been fully established. Transcriptome-wide association… read more here.

Keywords: breast cancer; intrinsic subtypes; wide association; association ... See more keywords

Abstract P1-06-02: Characterization of gene- and sample-level APOBEC mutagenesis enrichment with respect to intrinsic subtypes, tumor mutational burden, and immune composition in breast cancer

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Published in 2020 at "Cancer Research"

DOI: 10.1158/1538-7445.sabcs19-p1-06-02

Abstract: Introduction: APOlipoprotein B mRNA Editing enzyme Catalytic peptide-like, APOBEC, is a family of innate immune enzymes that catalyze cytosine to uracil deamination in single-stranded DNA, which lead to mutations in preferred trinucleotide contexts. APOBEC mutagenesis… read more here.

Keywords: cancer; apobec mutagenesis; intrinsic subtypes; breast cancer ... See more keywords

Abstract PO3-16-04: Distribution of intrinsic subtypes in endocrine-resistant and endocrine-sensitive breast cancer

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Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.sabcs23-po3-16-04

Abstract: Background Breast cancer (BC) is a heterogeneous disease that can be divided into intrinsic molecular subtypes. Among the four intrinsic subtypes, Luminal A and Luminal B are the most common and associated with the best… read more here.

Keywords: cancer; distribution; intrinsic subtypes; her2 ... See more keywords

Intrinsic subtypes of HER2-positive breast cancer and their associations with pathologic complete response (pCR) and outcomes: Findings from NSABP B-41, a randomized neoadjuvant trial.

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Published in 2018 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2018.36.15_suppl.580

Abstract: 580Background: NSABP B-41, randomly assigned 529 patients with HER2 positive breast cancer to receive neoadjuvant trastuzumab, lapatinib, or the combination, with weekly paclitaxel following doxorubicin and cyclophosphamide x 4. No significant difference in pCR was… read more here.

Keywords: her2 positive; breast; positive breast; breast cancer ... See more keywords