Divergent effects of intrinsically active MEK variants on developmental Ras signaling
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DOI: 10.1038/ng.3780
Abstract: Germline mutations in Ras pathway components are associated with a large class of human developmental abnormalities, known as RASopathies, that are characterized by a range of structural and functional phenotypes, including cardiac defects and neurocognitive… read more here.
Keywords: mek variants; intrinsically active; divergent effects; active mek ... See more keywords