Articles with "intron based" as a keyword



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Therapeutic applications of group I intron‐based trans‐splicing ribozymes

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Published in 2018 at "Wiley Interdisciplinary Reviews: RNA"

DOI: 10.1002/wrna.1466

Abstract: Since the breakthrough discovery of catalytic RNAs (ribozymes) in the early 1980s, valuable ribozyme‐based gene therapies have been developed for incurable diseases ranging from genetic disorders to viral infections and cancers. Ribozymes can be engineered… read more here.

Keywords: splicing ribozymes; group intron; gene; trans splicing ... See more keywords