Genetic Variations and Haplotypic Diversity in the Myostatin Gene of New Zealand Cattle Breeds.
Sign Up to like & getrecommendations! Published in 2020 at "Gene"
DOI: 10.1016/j.gene.2020.144400
Abstract: Myostatin (MSTN) is a circulating factor that is secreted by muscle cells, and that acts upon those cells to inhibit the proliferation of muscle fibres during pre-natal muscle growth. The Polymerase Chain Reaction (PCR) coupled… read more here.
Keywords: intron exon; myostatin; new zealand; gene ... See more keywords
Phylogenetic Analysis of 590 Species Reveals Distinct Evolutionary Patterns of Intron–Exon Gene Structures Across Eukaryotic Lineages
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DOI: 10.1093/molbev/msae248
Abstract: Abstract Introns are highly prevalent in most eukaryotic genomes. Despite the accumulating evidence for benefits conferred by the possession of introns, their specific roles and functions, as well as the processes shaping their evolution, are… read more here.
Keywords: evolution; 590 species; exon gene; gene structure ... See more keywords
Splicing Enhancers at Intron–Exon Borders Participate in Acceptor Splice Sites Recognition
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21186553
Abstract: Acceptor splice site recognition (3′ splice site: 3′ss) is a fundamental step in precursor messenger RNA (pre-mRNA) splicing. Generally, the U2 small nuclear ribonucleoprotein (snRNP) auxiliary factor (U2AF) heterodimer recognizes the 3′ss, of which U2AF35… read more here.
Keywords: recognition; intron exon; acceptor splice;
Transcriptome-Wide Detection of Intron/Exon Definition in the Endogenous Pre-mRNA Transcripts of Mammalian Cells and Its Regulation by Depolarization
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DOI: 10.3390/ijms231710157
Abstract: Pairing of splice sites across an intron or exon is the central point of intron or exon definition in pre-mRNA splicing with the latter mode proposed for most mammalian exons. However, transcriptome-wide pairing within endogenous… read more here.
Keywords: intron; exon definition; transcriptome wide; mammalian cells ... See more keywords
Developing an enhanced chimeric permuted intron-exon system for circular RNA therapeutics
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DOI: 10.7150/thno.98214
Abstract: Rationale: Circular RNA (circRNA) therapeutics hold great promise as an iteration strategy in messenger RNA (mRNA) therapeutics due to their inherent stability and durable protein translation capability. Nevertheless, the efficiency of RNA circularization remains a… read more here.
Keywords: rna; system; permuted intron; intron exon ... See more keywords