The novel activity of Argonautes in intron splicing: A transcriptome-wide survey in plants.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of plant physiology"
DOI: 10.1016/j.jplph.2022.153632
Abstract: The importance of the evolutionarily conserved Argonaute (AGO) proteins has been well recognized for their involvement in the RNA interference pathways. Recent discoveries in animals demonstrated that AGOs also participate in alternative splicing (AS). Motivated… read more here.
Keywords: ago proteins; intron splicing; activity argonautes; novel activity ... See more keywords
Pentatricopeptide repeat protein MID1 modulates nad2 intron 1 splicing and Arabidopsis development
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-58495-5
Abstract: As one of the best-studied RNA binding proteins in plant, pentatricopeptide repeats (PPRs) protein are mainly targeted to mitochondria and/or chloroplasts for RNA processing to regulate the biogenesis and function of the organelles, but its… read more here.
Keywords: nad2 intron; protein; intron splicing; intron ... See more keywords
Abstract A013: Minor intron splicing is critical for survival of lethal prostate cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.prca2023-a013
Abstract: The role of major intron splicing in PCa is well established and highly investigated. However, the equally important and impactful minor spliceosome (MiS) and minor intron splicing have remained underexplored in PCa. Here for the… read more here.
Keywords: intron; pca; minor intron; mis ... See more keywords
Inhibition of minor intron splicing reduces Na+ and Ca2+ channel expression and function in cardiomyocytes
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cell Science"
DOI: 10.1242/jcs.259191
Abstract: ABSTRACT Eukaryotic genomes contain a tiny subset of ‘minor class’ introns with unique sequence elements that require their own splicing machinery. These minor introns are present in certain gene families with specific functions, such as… read more here.
Keywords: expression function; intron splicing; channel expression; minor spliceosome ... See more keywords
Regulator of Chromosome Condensation 1-Domain Protein DEK47 Functions on the Intron Splicing of Mitochondrial Nad2 and Seed Development in Maize
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2021.695249
Abstract: In flowering plants, mitochondrial genes contain approximately 20–26 introns. Splicing of these introns is essential for mitochondrial gene expression and function. Recent studies have revealed that both nucleus- and mitochondrion-encoded factors are required for intron… read more here.
Keywords: seed; intron splicing; dek47; regulator chromosome ... See more keywords
Updated Progress on Group II Intron Splicing Factors in Plant Chloroplasts
Sign Up to like & getrecommendations! Published in 2022 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb44090290
Abstract: Group II introns are large catalytic RNAs (ribozymes) in the bacteria and organelle genomes of several lower eukaryotes. Many critical photosynthesis-related genes in the plant chloroplast genome also contain group II introns, and their splicing… read more here.
Keywords: intron; chloroplast; group; splicing factors ... See more keywords
Minor Intron Splicing from Basic Science to Disease
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DOI: 10.3390/ijms22116062
Abstract: Pre-mRNA splicing is an essential step in gene expression and is catalyzed by two machineries in eukaryotes: the major (U2 type) and minor (U12 type) spliceosomes. While the majority of introns in humans are U2… read more here.
Keywords: tissue specific; intron splicing; basic science; intron ... See more keywords
Organelle Genomes and Transcriptomes of Nymphaea Reveal the Interplay between Intron Splicing and RNA Editing
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22189842
Abstract: Posttranscriptional modifications, including intron splicing and RNA editing, are common processes during regulation of gene expression in plant organelle genomes. However, the intermediate products of intron-splicing, and the interplay between intron-splicing and RNA-editing were not… read more here.
Keywords: organelle genomes; rna editing; splicing rna; intron splicing ... See more keywords