Articles with "intronic enhancers" as a keyword



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Intronic enhancers of the human SNCA gene predominantly regulate its expression in brain in vivo

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Published in 2022 at "Science Advances"

DOI: 10.1126/sciadv.abq6324

Abstract: Evidence from patients with Parkinson’s disease (PD) and our previously reported α-synuclein (SNCA) transgenic rat model support the idea that increased SNCA protein is a substantial risk factor of PD pathogenesis. However, little is known… read more here.

Keywords: brain vivo; intronic enhancers; brain; snca gene ... See more keywords