Inula japonica ameliorated bleomycin-induced pulmonary fibrosis via inhibiting soluble epoxide hydrolase.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.104065
Abstract: Pulmonary fibrosis is a progressive, irreversible, and fatal fibrotic lung disease with a high mortality and morbidity, and commonly nonresponsive to conventional therapy. Inula japonica Thunb. is a traditional Chinese medicine, known as "Xuan Fu… read more here.
Keywords: fibrosis; blm induced; induced pulmonary; inula japonica ... See more keywords
Analysis of chemical composition of Inula japonica Thunb. extract and in vitro screening for anti-pulmonary fibrosis active components
Sign Up to like & getrecommendations! Published in 2020 at "Phytochemistry Letters"
DOI: 10.1016/j.phytol.2020.02.003
Abstract: Abstract Idiopathic pulmonary fibrosis (IPF) is a fatal and progressive lung disease with limited therapies, while transforming growth factor-β1 (TGF-β1) plays a central role in the pathogenesis of IPF. Here, we aim to investigate the… read more here.
Keywords: pulmonary fibrosis; japonica thunb; inula japonica;
Anti-inflammatory sesquiterpene dimers and diterpenes from the aerial part of Inula japonica.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Asian natural products research"
DOI: 10.1080/10286020.2021.1923012
Abstract: Phytochemical investigation on the 95% alcohol extract of the aerial part of Inula japonica led to the isolation of three new compounds, inulanolides F-G (1-2) and 17α-carboxaldehyde-ent-kaur-18-oic acid (3), together with four known compounds (4-7).… read more here.
Keywords: anti inflammatory; inula japonica; aerial part; part inula ... See more keywords