The role of invariant T cells in inflammation of the skin and airways
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-019-00740-9
Abstract: Invariant and semi-invariant T cells are emerging as important regulators of host environment interactions at barrier tissues such as the airway and skin. In contrast to conventional T cells, invariant natural killer T (iNKT) cells… read more here.
Keywords: skin airways; mait cells; inkt cells; inflammation ... See more keywords
Mucosal-associated invariant T cells and disease
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Immunology"
DOI: 10.1038/s41577-019-0191-y
Abstract: Mucosal-associated invariant T (MAIT) cells are unique innate-like T cells that bridge innate and adaptive immunity. They are activated by conserved bacterial ligands derived from vitamin B biosynthesis and have important roles in defence against… read more here.
Keywords: associated invariant; cells disease; mucosal associated; invariant cells ... See more keywords
Human mucosal-associated invariant T cells respond to Mucorales species in a MR1-dependent manner.
Sign Up to like & getrecommendations! Published in 2020 at "Medical mycology"
DOI: 10.1093/mmy/myaa103
Abstract: Activation of mucosal-associated invariant T cells (MAIT cells) by certain bacteria, viruses, and yeast is well studied, but the activation potential of filamentous moulds from the order Mucorales is not known. Here, we show a… read more here.
Keywords: mucorales species; associated invariant; mucosal associated; activation ... See more keywords
Mucosal Invariant T cells are Diminished in Very Early-Onset Inflammatory Bowel Disease
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Pediatric Gastroenterology and Nutrition"
DOI: 10.1097/mpg.0000000000003189
Abstract: Supplemental Digital Content is available in the text ABSTRACT Objectives: Very early-onset inflammatory bowel disease (VEO-IBD) arises in children less than 6 years old, a critical time for immunologic development and maturation of the intestinal… read more here.
Keywords: bowel disease; invariant cells; disease; inflammatory bowel ... See more keywords
The frequency of mucosal‐associated invariant T cells is selectively increased in dermatitis herpetiformis
Sign Up to like & getrecommendations! Published in 2017 at "Australasian Journal of Dermatology"
DOI: 10.1111/ajd.12456
Abstract: Mucosal‐associated invariant T (MAIT) cells are a novel subset of innate‐like T‐cells that are enriched in mucosal tissues. Their presence in human skin has only recently been recognised. We describe the expression of skin‐tropic molecules… read more here.
Keywords: associated invariant; frequency mucosal; mucosal associated; mucosal ... See more keywords
Mucosal-associated invariant T cells in digestive tract: Local guardians or destroyers?
Sign Up to like & getrecommendations! Published in 2023 at "Immunology"
DOI: 10.1111/imm.13653
Abstract: Mucosa-associated invariant T cells (MAIT) are a class of innate-like T lymphocytes mainly presenting CD8+ phenotype with a semi-invariant αβ T-cell receptor, which specifically recognises MR1-presented biosynthetic derivatives of riboflavin synthesis produced by various types… read more here.
Keywords: invariant cells; mucosal associated; associated invariant; digestive tract ... See more keywords
Mucosal-Associated Invariant T Cells as a Possible Target to Suppress Secondary Infections at COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01896
Abstract: Co-infections are of proven importance in the severity of respiratory diseases while their involvement in COVID-19 progression is still little discussed (1). However, one in seven patients with COVID-19 had secondary non-viral infections during hospitalization,… read more here.
Keywords: associated invariant; target suppress; possible target; mucosal associated ... See more keywords
Mucosal-associated invariant T cells in hematological malignancies: Current knowledge, pending questions
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1160943
Abstract: Non-classical HLA restricted T cell subsets such as γδ T and NK-T cells are showing promises for immune-based therapy of hematological malignancies. Mucosal-Associated Invariant T cells (MAIT) belong to this family of innate-like T cell… read more here.
Keywords: current knowledge; invariant cells; mucosal associated; associated invariant ... See more keywords