Invariant Natural Killer T cells resilience to paradoxical sleep deprivation-associated stress
Sign Up to like & getrecommendations! Published in 2020 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2020.08.018
Abstract: Although several studies demonstrate that stressful situations, such as sleep disturbances, negatively impact the innate and adaptive arms of the immune system, their influence on invariant Natural Killer T (iNKT) cells remains unclear. iNKT cells… read more here.
Keywords: sleep deprivation; inkt; invariant natural; natural killer ... See more keywords
Retinoic acid induction of CD1d expression primes chronic lymphocytic leukemia B cells for killing by CD8+ invariant natural killer T cells.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical immunology"
DOI: 10.1016/j.clim.2017.08.002
Abstract: Invariant natural killer T (iNKT) cells are cytotoxic T cells that respond to glycolipid antigens presented by CD1d. Therapeutic activation of iNKT cells with α-galactosylceramide (α-GalCer) can prevent and reverse tumor growth in mice and… read more here.
Keywords: cd1d expression; invariant natural; inkt cells; natural killer ... See more keywords
The protective function of invariant natural killer T cells in the relapse of experimental autoimmune uveoretinitis.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108406
Abstract: Experimental autoimmune uveoretinitis (EAU) in mice provides a useful platform to study the pathogenesis and experimental therapeutics of human uveitis. One often used EAU model employs C57BL/6 (B6) mice sensitized with a peptide residue having… read more here.
Keywords: invariant natural; natural killer; uveoretinitis; autoimmune uveoretinitis ... See more keywords
Study of the adoptive immunotherapy on rheumatoid arthritis with Thymus-derived invariant natural killer T cells.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2018.12.040
Abstract: BACKGROUND The therapeutic effect of adoptive infusion of specific thymus-derived invariant natural killer T (iNKT) cells in a mouse model of rheumatoid arthritis (RA) was observed, and the mechanism of cellular immunotherapy was preliminarily explored.… read more here.
Keywords: invariant natural; natural killer; thymus; thymus derived ... See more keywords
Invariant natural killer T cells treated with rapamycin or transforming growth factor-β acquire a regulatory function and suppress T effector lymphocytes
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Immunology"
DOI: 10.1038/cmi.2015.20
Abstract: Invariant natural killer T cells treated with rapamycin or transforming growth factor-β acquire a regulatory function and suppress T effector lymphocytes read more here.
Keywords: treated rapamycin; cells treated; rapamycin transforming; invariant natural ... See more keywords
The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells
Sign Up to like & getrecommendations! Published in 2017 at "Nature immunology"
DOI: 10.1038/ni.3644
Abstract: Invariant natural killer T cells (iNKT cells) are innate-like lymphocytes that protect against infection, autoimmune disease and cancer. However, little is known about the epigenetic regulation of iNKT cell development. Here we found that the… read more here.
Keywords: demethylase; lineage; inkt; invariant natural ... See more keywords
Endogenous lipid antigens for invariant natural killer T cells hold the reins in adipose tissue homeostasis
Sign Up to like & getrecommendations! Published in 2018 at "Immunology"
DOI: 10.1111/imm.12839
Abstract: The global obesity epidemic and its associated co‐morbidities, including type 2 diabetes, cardiovascular disease and certain types of cancers, have drawn attention to the pivotal role of adipocytes in health and disease. Besides their ‘classical’… read more here.
Keywords: lipid antigens; invariant natural; inkt cells; adipose tissue ... See more keywords
Activated invariant natural killer T cells infiltrate aortic tissue as key participants in abdominal aortic aneurysm pathology.
Sign Up to like & getrecommendations! Published in 2021 at "Immunology"
DOI: 10.1111/imm.13401
Abstract: Adaptive and innate immunity have been implicated in the pathogenesis of abdominal aortic aneurysm (AAA) and damage and remodeling in the tunica media are a focus of the aneurysm development, Thus, identification of key immune… read more here.
Keywords: invariant natural; aortic aneurysm; pathology; abdominal aortic ... See more keywords
Invariant natural killer T cells balance B cell immunity
Sign Up to like & getrecommendations! Published in 2021 at "Immunological Reviews"
DOI: 10.1111/imr.12938
Abstract: Invariant natural killer T (iNKT) cells mediate rapid immune responses which bridge the gap between innate and adaptive responses to pathogens while also providing key regulation to maintain immune homeostasis. Both types of important iNKT… read more here.
Keywords: natural killer; invariant natural; cell; inkt cells ... See more keywords
Activation of invariant natural killer T cells by alpha-galactosylceramide ameliorates doxorubicin-induced cardiotoxicity in mice
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Preventive Cardiology"
DOI: 10.1177/2047487319901208
Abstract: Title Activation of invariant natural killer T cells by alpha-galactosylceramide ameliorates doxorubicin-induced cardiotoxicity in mice Author(s) Obata, Yoshikuni; Ishimori, Naoki; Saito, Akimichi; Kinugawa, Shintaro; Yokota, Takashi; Takada, Shingo; Nakano, Ippei; Kakutani, Naoya; Yamanashi, Katsuma; Anzai,… read more here.
Keywords: cells alpha; cardiology; invariant natural; natural killer ... See more keywords
Expansion of invariant natural killer T cells from systemic lupus erythematosus patients by alpha-Galactosylceramide and IL-15
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0261727
Abstract: CD1d-restricted invariant natural killer T cells (iNKT cells) may play an important role in the pathogenesis of systemic lupus erythematosus (SLE). Interleukin (IL)-15 is a pro-inflammatory cytokine which is over-expressed in SLE patients. In the… read more here.
Keywords: galcer; inkt cells; inkt; sle patients ... See more keywords