Predicting microvascular invasion in HCC with ctDNA: What are the pitfalls?
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DOI: 10.1111/liv.14536
Abstract: We read with interest the paper "Preoperative evaluation of microvascular invasion with circulating tumor DNA in operable hepatocellular carcinoma" published in an upcoming issue of Liver International.1 It is an elegant study that looked at… read more here.
Keywords: invasion hcc; ctdna; invasion; microvascular invasion ... See more keywords
Knockdown of PHF5A Inhibits Migration and Invasion of HCC Cells via Downregulating NF-κB Signaling
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DOI: 10.1155/2019/1621854
Abstract: Background Inflammation is the major risk factor for the progression of hepatocellular carcinoma (HCC), and the nuclear factor-κB (NF-κB) signaling plays the central role in the inflammation process. However, the activated mechanism of NF-κB signaling… read more here.
Keywords: invasion hcc; phf5a; hcc; migration invasion ... See more keywords
Hypoxia Accelerates Aggressiveness of Hepatocellular Carcinoma Cells Involving Oxidative Stress, Epithelial-Mesenchymal Transition and Non-Canonical Hedgehog Signaling
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DOI: 10.1159/000485821
Abstract: Background/Aims: Hypoxic microenvironment, a common feature of hepatocellular carcinoma (HCC), can induce HIF-1α expression and promote the epithelial-mesenchymal transition (EMT) and invasion of cancer cells. However, the underlying molecular mechanisms have not fully elucidated. Methods:… read more here.
Keywords: invasion hcc; hcc; hcc cells; expression ... See more keywords