Metallodrugs: an approach against invasion and metastasis in cancer treatment
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13381
Abstract: Cancer is a heterogeneous and multifactorial disease that causes high mortality throughout the world; therefore, finding the most effective therapies is a major research challenge. Currently, most anticancer drugs present a limited number of well‐established… read more here.
Keywords: metastasis; metallodrugs approach; approach invasion; metastasis cancer ... See more keywords
Caspase‐3 regulates the migration, invasion and metastasis of colon cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31374
Abstract: Caspase‐3 (CASP3) is a major mediator of apoptosis activated during cellular exposure to cytotoxic drugs, radiotherapy or immunotherapy. It is often used as a marker for efficacy of cancer therapy. However, recent reports indicate that… read more here.
Keywords: cancer; caspase; invasion metastasis; colon cancer ... See more keywords
HPV16 infection promotes an M2 macrophage phenotype to promote the invasion and metastasis of esophageal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-021-02642-5
Abstract: High-risk human papillomavirus (HR-HPV) is an important risk factor for esophageal cancer. Macrophages constitute a crucial immune medium for regulating HPV-related tumors; however, the specific regulatory mechanisms remain unknown. Therefore, the purpose of our current… read more here.
Keywords: hpv16e6; infection; invasion metastasis; metastasis esophageal ... See more keywords
ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Physiology and Biochemistry"
DOI: 10.1007/s13105-019-00690-8
Abstract: N6-Methyladenosine (m6A) is the most common posttranscriptional modification of RNA and plays critical roles in cancer pathogenesis. However, the biological function of long noncoding RNA (lncRNA) methylation remains unclear. As a demethylase, ALKBH5 (alkylation repair… read more here.
Keywords: gastric cancer; alkbh5; methylation; invasion metastasis ... See more keywords
Sp1-mediated up-regulation of lnc00152 promotes invasion and metastasis of retinoblastoma cells via the miR-30d/SOX9/ZEB2 pathway
Sign Up to like & getrecommendations! Published in 2020 at "Cellular Oncology"
DOI: 10.1007/s13402-020-00522-8
Abstract: Purpose Previously, we found that long non-coding RNA (lncRNA) MEG3 may act as a tumour suppressor in retinoblastoma. Overall, however, little is known about the role of lncRNAs in retinoblastoma. Here, we aimed to determine… read more here.
Keywords: retinoblastoma cells; lnc00152; retinoblastoma; sox9 zeb2 ... See more keywords
Down-regulation of TRAF4 targeting RSK4 inhibits proliferation, invasion and metastasis in breast cancer xenografts.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.04.164
Abstract: Ribosomal S6 protein kinase 4 (RSK4) was known as a novel tumor suppressor gene, and the tumor necrosis factor receptor-associated factor 4 (TRAF4) was linked to carcinogenesis. The purpose of this study is to further… read more here.
Keywords: metastasis; invasion metastasis; proliferation invasion; traf4 ... See more keywords
CircRNF13 regulates the invasion and metastasis in lung adenocarcinoma by targeting miR-93-5p.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.04.069
Abstract: Circular RNAs (circRNAs) are a group of non-protein-coding RNAs that are generated from back-splicing. Recent evidence indicates that circRNAs play important roles in tissue development, gene regulation, and carcinogenesis. It was recently demonstrated that circular… read more here.
Keywords: lung adenocarcinoma; lung; circrnf13; invasion metastasis ... See more keywords
Roles of Arf6 in cancer cell invasion, metastasis and proliferation
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DOI: 10.1016/j.lfs.2017.06.008
Abstract: &NA; ADP‐ribosylation factor 6 (Arf6), a member of small GTPases ADP‐ribosylation factor (Arf) family, expresses widely in mammalian cells and mainly regulates the functions of membrane traffic and actin remodeling. Current studies indicated that the… read more here.
Keywords: invasion; invasion metastasis; metastasis proliferation; cancer ... See more keywords
The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
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DOI: 10.1038/s41467-021-24631-6
Abstract: Hypoxia plays a critical role in tumor progression including invasion and metastasis. To determine critical genes regulated by hypoxia that promote invasion and metastasis, we screen fifty hypoxia inducible genes for their effects on invasion.… read more here.
Keywords: maff; invasion; il11; stat3 ... See more keywords
FPR2 promotes invasion and metastasis of gastric cancer cells and predicts the prognosis of patients
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DOI: 10.1038/s41598-017-03368-7
Abstract: Formyl peptide receptor 2 (FPR2), a classical chemoattractant receptor of G-protein-coupled receptors, is reported to be involved in invasion and metastasis of some cancers, but the role of FPR2 in gastric cancer (GC) has not… read more here.
Keywords: metastasis; invasion metastasis; patients fpr2; gastric cancer ... See more keywords
An orthotopic mouse model of gastric cancer invasion and metastasis
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DOI: 10.1038/s41598-017-19025-y
Abstract: Gastric cancer is a leading cause of cancer death worldwide, with advanced stage being correlated to the level of tumour invasion and metastasis. Current research is heavily focused on the identification and development of efficacious… read more here.
Keywords: invasion; gastric cancer; cancer; invasion metastasis ... See more keywords