Correlation of serum galactomannan antigen with diagnosis and response to voriconazole in orbital/sino-orbital invasive aspergillosis
Sign Up to like & getrecommendations! Published in 2021 at "International Ophthalmology"
DOI: 10.1007/s10792-021-01848-4
Abstract: Localized form of orbit/sino-orbit invasive aspergillosis (IA) is a rare entity. Tissue sample is required for confirmatory diagnosis and initiation of treatment. Galactomannan (GM) is a heteropolysaccharide cell wall component released by growing hyphae of… read more here.
Keywords: treatment; ophthalmology; serum; invasive aspergillosis ... See more keywords
Local retrospective analysis of galactomannan cut-off values in bronchoalveolar lavage fluids for diagnosis of invasive aspergillosis
Sign Up to like & getrecommendations! Published in 2018 at "Folia Microbiologica"
DOI: 10.1007/s12223-018-0618-z
Abstract: Galactomannan antigen (GM) testing has been used for decades to screen immunocompromised patients for invasive aspergillosis (IA). Recent publications suggested that using a higher cut-off value than 0.5 in bronchoalveolar lavage fluid (BALF) could be… read more here.
Keywords: hematology; bronchoalveolar lavage; cut; cut values ... See more keywords
Use of Antifungals and Outcomes Among Inpatients at Risk of Invasive Aspergillosis or Mucormycosis in the USA: A Retrospective Cohort Study
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DOI: 10.1007/s40121-019-00267-4
Abstract: Prophylaxis and treatment of invasive aspergillosis (IA) and mucormycosis (IM) within a real-world US inpatient setting is undocumented since the introduction of isavuconazole. This retrospective medical record review aimed to describe characteristics, triazole use, and… read more here.
Keywords: outcomes among; prophylaxis treatment; use; treatment ... See more keywords
Evaluation of the Dynamiker® Fungus (1–3)-β-d-Glucan Assay for the Diagnosis of Invasive Aspergillosis in High-Risk Patients with Hematologic Malignancies
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DOI: 10.1007/s40121-022-00627-7
Abstract: The Dynamiker® Fungus (1–3)-β-d-glucan assay (DFA) allows the testing of samples in smaller batches compared to the well-established Fungitell® assay (FA) making the assay cost-effective in centers with small numbers of samples. Evaluations of its… read more here.
Keywords: glucan assay; invasive aspergillosis; dfa; fungus glucan ... See more keywords
The performance of galactomannan in combination with 1,3-β-D-glucan or aspergillus-lateral flow device for the diagnosis of invasive aspergillosis: Evidences from 13 studies.
Sign Up to like & getrecommendations! Published in 2019 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2018.08.005
Abstract: Galactomannan (GM), 1,3-β-D-glucan (BDG) and aspergillus-lateral flow device (LFD) are recognized as diagnostic tools for invasive aspergillosis (IA). The combined performance of these assays, however, is inconsistent in various studies. We undertook a meta-analysis of… read more here.
Keywords: flow device; aspergillus lateral; performance; invasive aspergillosis ... See more keywords
Microfluidic fluorescence immunosensor using ZnONFs for invasive aspergillosis determination
Sign Up to like & getrecommendations! Published in 2020 at "Microchemical Journal"
DOI: 10.1016/j.microc.2020.105371
Abstract: Abstract Galactomannan (GM) is a polysaccharide cell-wall component released by Aspergillus species, used as a biological marker for invasive aspergillosis (IA) screening. A fluorescence microfluidic immunosensor for GM detection was developed by using ZnO nanoflowers… read more here.
Keywords: fluorescence; microfluidic fluorescence; immunosensor; znonfs ... See more keywords
Invasive aspergillosis in a patient with end stage renal disease
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DOI: 10.1016/j.mmcr.2017.06.006
Abstract: Invasive aspergillosis caused by A. Fumigatus, almost occurs in immunocompromised hosts and has a poor prognosis. We report a case of invasive Aspergillosis in a 15-year-old boy with ESRD. He was initially diagnosed as lobar… read more here.
Keywords: aspergillosis; aspergillosis patient; patient end; stage renal ... See more keywords
Clinical-scale production of Aspergillus-specific T cells for the treatment of invasive aspergillosis in the immunocompromised host
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DOI: 10.1038/s41409-019-0501-9
Abstract: Invasive aspergillosis (IA) represents a leading cause of mortality in immunocompromised patients. Although adoptive immunotherapy with Aspergillus-specific T cells (Asp-STs) represents a promising therapeutic approach against IA, the complex and costly production limits its broader… read more here.
Keywords: production; aspergillus specific; specific cells; asp sts ... See more keywords
Systematic review and network meta-analysis of clinical outcomes associated with isavuconazole versus relevant comparators for patients with invasive aspergillosis
Sign Up to like & getrecommendations! Published in 2018 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2018.1502659
Abstract: Abstract Objectives: Voriconazole, amphotericin B (AmB) formulations, and isavuconazole are all included in guideline recommendations for treatment of patients with invasive aspergillosis (IA) but the relative efficacy of isavuconazole versus AmB formulations has not been… read more here.
Keywords: patients invasive; amb; invasive aspergillosis; meta analysis ... See more keywords
Point-of-care diagnostics for invasive aspergillosis: nearing the finish line
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2020.1820864
Abstract: ABSTRACT Introduction The spectrum of disease caused by Aspergillus spp. is dependent on the immune system of the host, with invasive aspergillosis (IA) its most severe manifestation. Early and reliable diagnosis of Aspergillus disease is… read more here.
Keywords: point care; point; lateral flow; invasive aspergillosis ... See more keywords
Stimulating the autophagic-lysosomal axis enhances host defense against fungal infection in a zebrafish model of invasive Aspergillosis
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2090727
Abstract: ABSTRACT The increasing prevalence of antifungal-resistant human pathogenic fungi, particularly azole-resistant Aspergillus fumigatus, is a life-threatening challenge to the immunocompromised population. Autophagy-related processes such as LC3-associated phagocytosis have been shown to be activated in the… read more here.
Keywords: host; invasive aspergillosis; model; fungal infection ... See more keywords