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Published in 2022 at "Journal of hospital medicine"
DOI: 10.1002/jhm.12956
Abstract: BACKGROUND Febrile infants are at risk for invasive bacterial infections (IBIs) (i.e., bacteremia and bacterial meningitis), which, when undiagnosed, may have devastating consequences. Current IBI predictive models rely on serum biomarkers, which may not provide…
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Keywords:
invasive bacterial;
febrile infants;
age;
bacterial infections ... See more keywords
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Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.1981
Abstract: Abstract Background Serious infections remain the leading cause of death in the first year of life. Sepsis in neonatal intensive care units is well described but infants with bacterial infections presenting from the community has…
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Keywords:
new zealand;
community;
invasive bacterial;
streptococcus ... See more keywords
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Published in 2023 at "Journal of medical microbiology"
DOI: 10.1099/jmm.0.001644
Abstract: Introduction. In 2009, the World Health Organization (WHO) established the Global Invasive Bacterial Vaccine Preventable Disease (IB-VPD) Surveillance Network (GISN) to monitor the global burden and aetiology of bacterial meningitis, pneumonia and sepsis caused by…
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Keywords:
programme;
health organization;
bacterial vaccine;
invasive bacterial ... See more keywords
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Published in 2022 at "eLife"
DOI: 10.1101/2022.02.18.22271173
Abstract: Invasive bacterial disease is a major cause of morbidity and mortality in African children. Despite being caused by diverse pathogens, children with sepsis are clinically indistinguishable from one another. In spite of this, most genetic…
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Keywords:
kenyan children;
invasive bacterial;
birc6 modifies;
bacterial disease ... See more keywords
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Published in 2023 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2022-325281
Abstract: Objective To determine the incidence and clinical predictors of invasive bacterial infection (IBI) in well-appearing children who present to the emergency department (ED) with fever and petechiae. Design A prospective, observational, multicentre study was conducted…
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Keywords:
rash;
invasive bacterial;
children fever;
emergency department ... See more keywords
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Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2022-062473
Abstract: Introduction Young febrile infants are at higher risk of invasive bacterial infections (IBIs) compared with older children. The clinical features of IBI are subtle in this cohort mandating that clinicians take a cautious approach to…
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Keywords:
review;
pct;
accuracy;
invasive bacterial ... See more keywords
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Published in 2019 at "Journal of Innate Immunity"
DOI: 10.1159/000500545
Abstract: Streptococcus pneumoniae and Neisseria meningitidis are pathogens that frequently colonize the nasopharynx in an asymptomatic manner but are also a cause of invasive bacterial infections mainly in young children. The complement system plays a crucial…
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Keywords:
variants complement;
genetic variants;
complement system;
invasive bacterial ... See more keywords
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Published in 2020 at "Pediatrics"
DOI: 10.1542/peds.2020-1571
Abstract: Invasive bacterial infections and adverse events are uncommon in afebrile infants with clinician-diagnosed acute otitis media. OBJECTIVES: To determine the prevalence of invasive bacterial infections (IBIs) and adverse events in afebrile infants with acute otitis…
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Keywords:
otitis media;
afebrile infants;
acute otitis;
invasive bacterial ... See more keywords
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Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21186976
Abstract: Severe anaemia and invasive bacterial infections are common causes of childhood sickness and death in sub-Saharan Africa. Accumulating evidence suggests that severely anaemic African children may have a higher risk of invasive bacterial infections. However,…
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Keywords:
severe anaemia;
invasive bacterial;
bacterial infections;
risk invasive ... See more keywords