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Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.114201
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Invasive candidiasis (IC) mainly occurs in patients who are immunocompromised or immunosuppressed; those who have undergone trauma, medical device implantation, organ transplantation; and patients with neutropenia. The mortality rate of IC is ∼40%,…
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Keywords:
invasive candidiasis;
medicine;
number;
compound ... See more keywords
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Published in 2017 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2017.1354824
Abstract: Abstract Objective: To investigate the epidemiology, treatment, length of stay (LOS) and costs for neonatal and pediatric inpatients with invasive candidiasis (IC). Methods: The Cerner Health Facts Database was used to assess inpatients (2005–2014) identified…
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Keywords:
invasive candidiasis;
candidiasis;
among hospitalized;
candidemia invasive ... See more keywords
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Published in 2022 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkac344
Abstract: Abstract Objectives Enrolment of subjects to clinical trials investigating novel drugs for infectious diseases is an ongoing challenge. In this study, we evaluate factors associated with non-enrolment in treatment trials for invasive candidiasis. Methods We…
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Keywords:
trials invasive;
clinical trials;
candidiasis;
restore ... See more keywords
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Published in 2021 at "Medical mycology"
DOI: 10.1093/mmy/myab069
Abstract: The impact of invasive candidiasis (IC) on the outcomes in the non-conventional high-risk cirrhosis population is poorly characterized. Therefore, we reviewed the outcomes and their influencing factors in cirrhosis patients with IC. PubMed, Embase, Ovid,…
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Keywords:
cirrhosis patients;
invasive candidiasis;
high mortality;
cirrhosis ... See more keywords
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Published in 2017 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofx163.024
Abstract: Abstract Background Breakthrough invasive candidiasis (bIC) has been described in adults, but the epidemiology and outcomes in children are unknown. Methods Retrospective cohort analysis of children diagnosed with IC from 9/1/09 to 1/30/17. bIC was…
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Keywords:
invasive candidiasis;
breakthrough invasive;
bic;
epidemiology ... See more keywords
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Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.373
Abstract: Abstract Background While 50% of invasive candidiasis (IC) has historically been caused by C. albicans, the changing epidemiology and rise in drug-resistant Candida necessitates understanding the contribution of specific Candida species to IC. To date,…
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Keywords:
invasive candidiasis;
record;
blood;
species distribution ... See more keywords
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Published in 2019 at "Critical Care Medicine"
DOI: 10.1097/01.ccm.0000551399.08737.0e
Abstract: Learning Objectives: Previous studies have evaluated risk factors for invasive candidiasis (IC) in critically ill patients. However, risk factors have not been evaluated exclusively in critically ill patients after abdominal surgery, a population that could…
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Keywords:
invasive candidiasis;
risk;
risk factors;
intra abdominal ... See more keywords
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Published in 2019 at "Current Opinion in Infectious Diseases"
DOI: 10.1097/qco.0000000000000594
Abstract: PURPOSE OF REVIEW We review the performance of culture-independent diagnostic tests (CIDTs), including β-D-glucan (BDG), polymerase chain reaction (PCR) and T2Candida, in diagnosing invasive candidiasis, their potential roles in patient management, and unintended consequences of…
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Keywords:
invasive candidiasis;
t2candida;
candidiasis;
prime time ... See more keywords
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Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01113-22
Abstract: Candida bloodstream infections are associated with high attributable mortality, where early initiation of adequate antifungal therapy is important to increase survival in critically ill patients. The exposure variability of micafungin, a first-line agent used for…
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Keywords:
ill patients;
critically ill;
sampling strategies;
invasive candidiasis ... See more keywords
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Published in 2017 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01398-17
Abstract: ABSTRACT The estimated attributable mortality rate for invasive candidiasis (IC) in the intensive care unit (ICU) setting varies from 30 to 40%. Physiological changes in critically ill patients may affect the distribution and elimination of…
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Keywords:
micafungin;
invasive candidiasis;
ill patients;
liter ... See more keywords
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Published in 2018 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01572-18
Abstract: Rezafungin (CD101) is a novel echinocandin under development for once-weekly intravenous (i.v.) dosing. We evaluated the pharmacodynamics (PD) of rezafungin against 4 Candida auris strains, using the neutropenic mouse invasive candidiasis model. ABSTRACT Rezafungin (CD101)…
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Keywords:
invasive candidiasis;
rezafungin;
mouse invasive;
candida auris ... See more keywords