Evolution of antifungals for invasive mold infections in immunocompromised hosts, then and now
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2023.2207821
Abstract: ABSTRACT Introduction The current armamentarium of antifungal agents for invasive mold infections (IMI) has dramatically improved over the last 50 years. Existing therapies are, however, associated with toxicities, drug interactions, and, in some cases, therapeutic failures.… read more here.
Keywords: invasive mold; mold infections; infections immunocompromised; antifungals invasive ... See more keywords
Invasive mold infection of the gastrointestinal tract: A case series of 22 immunocompromised patients from a single academic center
Sign Up to like & getrecommendations! Published in 2022 at "Medical Mycology"
DOI: 10.1093/mmy/myac007
Abstract: Abstract Invasive mold infection (IMI) of the gastrointestinal (GI) tract is a rare complication in immunocompromised patients that carries a high mortality rate. It is most often described in the setting of disseminated disease. Early… read more here.
Keywords: invasive mold; mold infection; infection; immunocompromised patients ... See more keywords
1153. Characterization of Invasive Mold Infections in Acute Leukemia and Hematopoietic Stem Cell Transplant Recipient Patients and Risk Factors for Mortality - a Single Center Experience
Sign Up to like & getrecommendations! Published in 2020 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaa439.1339
Abstract: Invasive mold infections (IMIs) remain a significant cause of morbidity and mortality in patients with acute leukemia (AL) and those undergoing hematopoietic stem cell transplantation (HSCT). We describe the epidemiology of IMIs, the incidence of… read more here.
Keywords: invasive mold; diagnosis; mold infections; mortality ... See more keywords
Isavuconazole for the Treatment of Invasive Mold Disease in Solid Organ Transplant Recipients: A Multicenter Study on Efficacy and Safety in Real-life Clinical Practice
Sign Up to like & getrecommendations! Published in 2022 at "Transplantation"
DOI: 10.1097/tp.0000000000004312
Abstract: Background. Isavuconazole has theoretical advantages over other mold-active triazoles for the treatment of invasive aspergillosis and mucormycosis after solid organ transplantation (SOT). The available clinical experience, nevertheless, is scarce. Methods. We performed a retrospective study… read more here.
Keywords: invasive mold; mold disease; therapy; treatment invasive ... See more keywords
Therapeutic Challenges of Non-Aspergillus Invasive Mold Infections in Immunosuppressed Patients
Sign Up to like & getrecommendations! Published in 2019 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01244-19
Abstract: While Aspergillus spp. remain the major cause of invasive mold infections in hematologic cancer patients and transplant recipients, other opportunistic molds, such as Mucorales, Fusarium, and Scedosporium spp. are increasingly encountered in an expanding population… read more here.
Keywords: invasive mold; spp; non aspergillus; mold infections ... See more keywords
Ibrexafungerp, a Novel Triterpenoid Antifungal in Development for the Treatment of Mold Infections
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8111121
Abstract: Molds are ubiquitous in the environment, and immunocompromised patients are at substantial risk of morbidity and mortality due to their underlying disease and the resistance of pathogenic molds to currently recommended antifungal therapies. This combination… read more here.
Keywords: invasive mold; mold infections; ibrexafungerp novel; fungal infections ... See more keywords