Heterogeneous induction of an invasive phenotype in prostate cancer cells by coculturing with patient‐derived fibroblasts
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29893
Abstract: Prostate cancer (PCa) cells frequently invade the surrounding stroma, leading to heterogeneous formation of structural atypia. The surrounding stroma contains multiple functionally diverse populations of fibroblasts that trigger numerous changes in PCa cells including motility.… read more here.
Keywords: pcprf; fibroblast lines; patient derived; invasive phenotype ... See more keywords
Detection and Enumeration of Circulating Tumor Cells with Invasive Phenotype.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-55947-6_7
Abstract: Circulating tumor cells (CTCs) disseminate from solid primary cancers into the peripheral blood and lymphatic vessels and can lead to metastatic tumor development; thus, CTC assays are an important clinical tool for monitoring progression and… read more here.
Keywords: detection; tumor cells; circulating tumor; invasive phenotype ... See more keywords
A robust strategy for proteomic identification of biomarkers of invasive phenotype complexed with extracellular heat shock proteins
Sign Up to like & getrecommendations! Published in 2019 at "Cell Stress and Chaperones"
DOI: 10.1007/s12192-019-01041-8
Abstract: As an extension of their orchestration of intracellular pathways, secretion of extracellular heat shock proteins (HSPs) is an emerging paradigm of homeostasis imperative to multicellular organization. Extracellular HSP is axiomatic to the survival of cells… read more here.
Keywords: phenotype; shock proteins; heat shock; invasive phenotype ... See more keywords
Abstract 129: Tumor-associated macrophages secrete CCL2 and induce the invasive phenotype of human breast epithelial cells through upregulation of ERO1-alpha and MMP-9
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-129
Abstract: Tumor-associated macrophages (TAMs) are major components of tumor microenvironment that promote invasion and metastasis of cancer cells. In this study, we investigated the effect of TAMs on phenotypic conversion of non-neoplastic MCF10A human breast epithelial… read more here.
Keywords: mmp; ero1 alpha; tumor; breast ... See more keywords