Inverse screening of Simvastatin kinase targets from glioblastoma druggable kinome
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DOI: 10.1016/j.compbiolchem.2020.107243
Abstract: The statin drug Simvastatin is a HMG-CoA reductase inhibitor that has been widely used to lower blood lipid. However, the drug is clinically observed to reposition a significant suppressing potency on glioblastoma (GBM) by unexpectedly… read more here.
Keywords: inverse screening; simvastatin; kinase; druggable kinome ... See more keywords