Inverse In Vitro Selection Enables Comprehensive Analysis of Cross‐Chiral L‐Aptamer Interactions
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DOI: 10.1002/cbic.202200520
Abstract: Aptamers composed of mirror‐image L‐(deoxy)ribose nucleic acids, referred to as L‐aptamers, are a promising class of RNA‐binding reagents. Yet, the selectivity of cross‐chiral interactions between L‐aptamers and their RNA targets remain poorly characterized, limiting the… read more here.
Keywords: vitro selection; cross chiral; aptamer; inverse vitro ... See more keywords