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Synthesis and Evaluation of New Fluorine-18 Labeled Verapamil Analogs To Investigate the Function of P-Glycoprotein in the Blood–Brain Barrier

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Published in 2017 at "ACS Chemical Neuroscience"

DOI: 10.1021/acschemneuro.7b00086

Abstract: P-glycoprotein is an efflux transporter located in the blood–brain barrier. (R)-[11C]Verapamil is widely used as a PET tracer to investigate its function in patients with epilepsy, Alzheimer’s disease, and other neurodegenerative diseases. Currently it is… read more here.

Keywords: blood brain; new fluorine; fluorine labeled; investigate function ... See more keywords