Methods to Investigate the Molecular Basis of Progranulin Action on Neurons In Vivo Using Caenorhabditis elegans.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8559-3_13
Abstract: The C. elegans nematode is a powerful genetic tool for the study of aging, developmental biology, and neurodegenerative diseases. They are a small and simple model, but its well-known genome and presence of many human… read more here.
Keywords: molecular basis; biology; investigate molecular; basis progranulin ... See more keywords
DARTpaths, an in silico platform to investigate molecular mechanisms of compounds
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DOI: 10.1093/bioinformatics/btac767
Abstract: Abstract Summary Xpaths is a collection of algorithms that allow for the prediction of compound-induced molecular mechanisms of action by integrating phenotypic endpoints of different species; and proposes follow-up tests for model organisms to validate… read more here.
Keywords: silico platform; dartpaths silico; molecular mechanisms; platform investigate ... See more keywords