Articles with "investigating structural" as a keyword



Investigating of structural, morphology, optical, transport and magnetic properties of Mg1−xCuxO

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Published in 2019 at "Indian Journal of Physics"

DOI: 10.1007/s12648-018-01369-4

Abstract: Effect of Cu2+ content on different properties was investigated. Mg1−xCuxO (0.05 ≤ x ≤ 0.2) powder was prepared via solid-state reaction. The samples were examined by X-ray diffraction, and the results were analyzed by using Full Prof program by… read more here.

Keywords: content; increasing content; mg1 xcuxo; increase ... See more keywords
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Investigating structural aspects of Pyridopyrimidinone derivatives, an important precursor in medicinal chemistry

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Published in 2021 at "Journal of Molecular Structure"

DOI: 10.1016/j.molstruc.2020.129040

Abstract: Abstract Pyridopyrimidinones are class of heterocyclic compounds which serves as important precursors in organic transformation and medicinal chemistry. In the current work three derivatives of pyrido[1,2-a]pyrimidine-3-carboxylates (1, 2 and 3) has been synthesized and characterized… read more here.

Keywords: investigating structural; medicinal chemistry; chemistry; pyrimidine carboxylates ... See more keywords

Investigating the structural modifications in LaAlYbCuO

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Published in 2019 at "Results in Physics"

DOI: 10.1016/j.rinp.2019.01.058

Abstract: Abstract In this research, we seek a new superconducting candidate LaAlYbCuO based on the need to improve upon the lanthanum cuprates framework. LaAlYbCuO high temperature superconductor was prepared by standard solid-state reaction. The characterization was… read more here.

Keywords: microscopy; structural modifications; electron; investigating structural ... See more keywords
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Investigating the structural transitions of proteins during dissolution by mass spectrometry.

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Published in 2017 at "Talanta"

DOI: 10.1016/j.talanta.2016.11.018

Abstract: An appropriate solvent environment is essential for the implementation of biological functions of proteins. Interactions between protein residues and solvent molecules are of great importance for proteins to maintain their active structure and catalyze biochemical… read more here.

Keywords: investigating structural; proteins dissolution; structural transitions; transitions proteins ... See more keywords

Tale of Two Polymorphs: Investigating the Structural Differences and Dynamic Relationship between Nirmatrelvir Solid Forms (Paxlovid).

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Published in 2024 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.3c01074

Abstract: Two anhydrous polymorphs of the novel antiviral medicine nirmatrelvir were discovered during the development of Paxlovid, Pfizer's oral Covid-19 treatment. A comprehensive experimental and computational approach was necessary to distinguish the two closely related polymorphs,… read more here.

Keywords: tale two; polymorphs; investigating structural; two polymorphs ... See more keywords

Investigating the Structural and Functional Consequences of Pathogenic SNPs on Human VEGFA Dimer: Insights from Molecular Dynamics Study

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Published in 2025 at "ACS Omega"

DOI: 10.1021/acsomega.5c07106

Abstract: Vascular endothelial growth factor A (VEGFA) is a key regulator of angiogenesis. It forms a homodimer and binds to VEGF receptors to activate signaling pathways important for blood vessel growth and maintenance. In this study,… read more here.

Keywords: vegfa dimer; functional consequences; investigating structural; molecular dynamics ... See more keywords

Investigating Structural Property Relationships to Enable Repurposing of Pharmaceuticals as Zinc Ionophores

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Published in 2021 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics13122032

Abstract: The importance of zinc in biology has gained greater recognition in recent years due to its essential contributions to the function of many endogenous enzymes. Disruption of zinc homeostasis may be useful in treating pathological… read more here.

Keywords: ionophoric activity; investigating structural; structural property; zinc ionophores ... See more keywords