Allosteric Methods and Their Applications: Facilitating the Discovery of Allosteric Drugs and the Investigation of Allosteric Mechanisms.
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DOI: 10.1021/acs.accounts.8b00570
Abstract: Allostery, or allosteric regulation, is the phenomenon in which protein functional activity is altered by the binding of an effector at an allosteric site that is topographically distinct from the orthosteric, active site. As one… read more here.
Keywords: allosteric drugs; allosteric sites; discovery; investigation allosteric ... See more keywords