Synthesis and Bioactivity Investigation of the Individual Components of Cyclic Lipopeptide Antibiotics.
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DOI: 10.1021/acs.jmedchem.7b01367
Abstract: In this paper, 26 natural polymyxin components and a new derivative S2 were synthesized, and their differences in efficacy and toxicity have been investigated. Almost all of the synthesized components showed strong activity against both… read more here.
Keywords: investigation individual; components cyclic; toxicity; individual components ... See more keywords