Further investigation of inhibitors of MRSA pyruvate kinase: Towards the conception of novel antimicrobial agents.
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DOI: 10.1016/j.ejmech.2016.09.018
Abstract: Several novel series of compounds were synthesized and evaluated as inhibitors of methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase (PK). PK has been identified as a highly interconnected essential 'hub' protein in MRSA, with structural features… read more here.
Keywords: novel antimicrobial; pyruvate kinase; inhibitors mrsa; investigation inhibitors ... See more keywords
The Investigation of Nfκb Inhibitors to Block Cell Proliferation in OSCC Cells Lines
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DOI: 10.2174/0109298673309489240816063313
Abstract: Background Oral cancers, with oral squamous cell carcinoma (OSCC) as the predominant type, have a significant impact on morbidity and mortality rates. Therefore, targeting the NFκB pathway shows promise in cancer therapy. Materials and Methods… read more here.
Keywords: ly2409881 mln4924; cell proliferation; investigation inhibitors; cell ... See more keywords