An investigation into the molecular basis of cancer comorbidities in coronavirus infection
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12984
Abstract: Comorbidities in COVID‐19 patients often worsen clinical conditions and may represent death predictors. Here, the expression of five genes, known to encode coronavirus receptors/interactors (ACE2, TMPRSS2, CLEC4M, DPP4 and TMPRSS11D), was investigated in normal and… read more here.
Keywords: investigation molecular; coronavirus receptors; infection; expression ... See more keywords
AI-based investigation of molecular biomarkers of longevity
Sign Up to like & getrecommendations! Published in 2020 at "Biogerontology"
DOI: 10.1007/s10522-020-09890-y
Abstract: In this paper, I build deep neural networks of various structures and hyperparameters in order to predict human chronological age based on open-access biochemical indicators and their specifications from the NHANES database. In total, 1152… read more here.
Keywords: neural networks; investigation molecular; biomarkers longevity; age ... See more keywords
Theoretical investigation of the molecular structure, vibrational spectra, thermodynamic and nonlinear optical properties of 4, 5-dibromo-2, 7dinitro- fluorescein
Sign Up to like & getrecommendations! Published in 2020 at "Optical and Quantum Electronics"
DOI: 10.1007/s11082-020-02396-4
Abstract: In this article, we have investigated the structural analysis, thermodynamics, nonlinear properties and vibrational analysis of 4′,5′-dibromo-2′,7′-dinitro-3′,6′-dihydroxyspiro[isobenzofuran-1(3H),9′-[9H]xanthan]-3-one. We used the restricted Hartree–Fock and density functional theory (PBE1PBE, MPW1PW91, B3PW91 and B3LYP) approach to calculate the… read more here.
Keywords: energy; investigation molecular; molecular structure; theoretical investigation ... See more keywords
Investigation of molecular and mesoscale clusters in undersaturated glycine aqueous solutions
Sign Up to like & getrecommendations! Published in 2019 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2019.123633
Abstract: Abstract In this work DLS, NTA, SAXS and NMR were used to investigate populations, size distributions and structure of clusters in undersaturated aqueous solutions of glycine. Molecular and colloidal scale (mesoscale) clusters with radii around… read more here.
Keywords: investigation molecular; mesoscale clusters; aqueous solutions; molecular mesoscale ... See more keywords
Theoretical investigation of the molecular properties of PtBO and PdBO
Sign Up to like & getrecommendations! Published in 2017 at "Computational and Theoretical Chemistry"
DOI: 10.1016/j.comptc.2017.03.015
Abstract: Abstract The molecular properties of the ground and low-lying excited states of PtBO and PdBO were calculated using density functional theory and high-level ab initio methods. Spin-orbit coupling was also considered to identify the true… read more here.
Keywords: molecular properties; investigation molecular; ptbo pdbo; theoretical investigation ... See more keywords
Investigation into molecular properties of pristine corannulene and its analogs with B/N-doping at hub location
Sign Up to like & getrecommendations! Published in 2020 at "Computational and Theoretical Chemistry"
DOI: 10.1016/j.comptc.2020.113002
Abstract: Abstract A suitable approach to modify the fundamental nature of π-conjugated systems is to embed of the elements of the main groups into their framework, giving rise to attractive electronic and optoelectronic properties. We have… read more here.
Keywords: properties pristine; investigation molecular; hub; molecular properties ... See more keywords
Investigation of the molecular characteristics of bisindole inhibitors as HIV-1 glycoprotein-41 fusion inhibitors.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.10.048
Abstract: In previous work, we described 6-6'-bisindole compounds targeting a hydrophobic pocket on the N-heptad repeat region of viral glycoprotein-41 as effective inhibitors of HIV-1 fusion. Two promising compounds with sub-micromolar IC50's contained a benzoic acid… read more here.
Keywords: characteristics bisindole; investigation molecular; benzoic acid; molecular characteristics ... See more keywords
Spectroscopic and molecular docking approaches for the investigation of molecular interactions between herbicide sulfosulfuron and bovine serum albumin
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2017.1375991
Abstract: Serum albumins are provided with manifold biological and pharmacokinetic functions, they can carry large variety of endogenous and exogenous compounds, such as nutrients, metabolites, fatty acids a... read more here.
Keywords: investigation molecular; approaches investigation; serum; docking approaches ... See more keywords
Case Report: Investigation and molecular genetic diagnosis of familial hypomagnesaemia
Sign Up to like & getrecommendations! Published in 2019 at "F1000Research"
DOI: 10.12688/f1000research.19006.2
Abstract: Genetic mutations causing familial hypomagnesaemia syndromes are well-recognised. Affected patients can present with severe symptoms of hypomagnesaemia, such as seizures or cardiac arrhythmia. We report an affected child, from a consanguineous family, who presented in… read more here.
Keywords: hypomagnesaemia; report investigation; investigation molecular; familial hypomagnesaemia ... See more keywords
Investigation of the Molecular Mechanism of Coagulopathy in Severe and Critical Patients With COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.762782
Abstract: Coagulopathy is a frequently reported finding in the pathology of coronavirus disease 2019 (COVID-19); however, the molecular mechanism, the involved coagulation factors, and the role of regulatory proteins in homeostasis are not fully investigated. We… read more here.
Keywords: mechanism coagulopathy; critical patients; molecular mechanism; investigation molecular ... See more keywords
In silico investigation of molecular networks linking gastrointestinal diseases, malnutrition, and sarcopenia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.989453
Abstract: Malnutrition is a common primary or secondary complication in gastrointestinal diseases. The patient’s nutritional status also influences muscle mass and function, which can be impaired up to the degree of sarcopenia. The molecular interactions in… read more here.
Keywords: gastrointestinal diseases; silico investigation; malnutrition; investigation molecular ... See more keywords