Quantum Mechanical Investigation of the G-Quadruplex Systems of Human Telomere
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DOI: 10.1021/acsomega.8b01678
Abstract: The three G-quadruplexes involved in the human telomere have been studied with an accurate quantum mechanical approach, and the possibility of reducing them to a simpler model has been tested. The similarities and the differences… read more here.
Keywords: investigation quadruplex; quadruplex systems; mechanical investigation; cavity ... See more keywords
Synthesis and Investigation of the G-Quadruplex Binding Properties of Kynurenic Acid Derivatives with a Dihydroimidazoquinoline-3,5-dione Core
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DOI: 10.3390/molecules27092791
Abstract: G-quadruplexes are secondary structures originating from nucleic acid regions rich in guanines, which are well known for their involvement in gene transcription and regulation and DNA damage repair. In recent studies from our group, kynurenic… read more here.
Keywords: quadruplex binding; kynurenic acid; quadruplex; investigation quadruplex ... See more keywords