Investigation on 2',3'-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists.
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DOI: 10.1021/acsmedchemlett.8b00524
Abstract: Antagonists of the purinergic P2X3 receptors represent promising drugs for the treatment of inflammation and pain. The ATP derivative 2',3'-O-(2,4,6-trinitrophenyl)-ATP (TNP-ATP) has been described as a potent competitive inhibitor of this receptor. In this work,… read more here.
Keywords: investigation substituted; receptor; p2x3; p2x3 receptor ... See more keywords