Investigations on 16-Arylideno Steroids as a New Class of Neuroprotective Agents for the Treatment of Alzheimer's and Parkinson's Diseases.
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DOI: 10.1021/acschemneuro.6b00313
Abstract: Neuroinflammatory mechanisms mediated by activated glial and cytokines (TNF-α, IL-1β) might contribute to neuronal degeneration leading to Alzheimer's (AD) and Parkinson's disease (PD). Lipopolysaccharide (LPS) is an inflammogen derived from the cell wall of Gram-negative… read more here.
Keywords: steroidal derivatives; treatment; investigations arylideno; alzheimer parkinson ... See more keywords