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Published in 2021 at "Chemmedchem"
DOI: 10.1002/cmdc.202100042
Abstract: Metallo‐β‐lactamases (MBLs) are zinc‐dependent bacterial enzymes that inactivate essentially all classes of β‐lactam antibiotics including last‐resort carbapenems. At present there are no clinically approved MBL inhibitors, and in order to develop such agents it is…
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Keywords:
zinc;
investigations metallo;
mechanistic investigations;
inhibition ... See more keywords