P2X7Rs are involved in cell death, growth and cellular signaling in primary human osteoblasts.
Sign Up to like & getrecommendations! Published in 2017 at "Bone"
DOI: 10.1016/j.bone.2016.11.011
Abstract: The ionotropic ATP-gated P2X7 receptor (P2X7R) is involved in the regulation of many physiological functions including bone metabolism. Several studies on osteoblasts from rodents and human osteoblast-like cell lines have addressed the expression and function… read more here.
Keywords: p2x7rs involved; bone; involved cell; human osteoblasts ... See more keywords
Signaling pathways involved in cell cycle arrest during the DNA breaks.
Sign Up to like & getrecommendations! Published in 2021 at "DNA repair"
DOI: 10.1016/j.dnarep.2021.103047
Abstract: Our genome bears tens of thousands of harms and devastations per day; In this regard, numerous sophisticated and complicated mechanisms are embedded by our cells in furtherance of remitting an unchanged and stable genome to… read more here.
Keywords: signaling pathways; dna; cell cycle; pathways involved ... See more keywords
Cytoplasmic TDP-43 is involved in cell fate during stress recovery.
Sign Up to like & getrecommendations! Published in 2021 at "Human molecular genetics"
DOI: 10.1093/hmg/ddab227
Abstract: TAR DNA binding protein 43 (TDP-43) is an RNA processing protein central to the pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Nuclear TDP-43 mislocalises in patients to the cytoplasm, where it forms… read more here.
Keywords: recovery; tdp; stress; tdp involved ... See more keywords