Na/K Pump Mutations Associated with Primary Hyperaldosteronism Cause Loss of Function.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b00051
Abstract: Primary hyperaldosteronism (Conn's syndrome), a common cause of secondary hypertension, is frequently produced by unilateral aldosterone-producing adenomas that carry mutations in ion-transporting genes, including ATP1A1, encoding the Na/K pump's α1 subunit. Whether Na/K pump mutant-mediated… read more here.
Keywords: hyperaldosteronism; pump; primary hyperaldosteronism; inward currents ... See more keywords
Resveratrol activates GABAA and/or glycine receptors on substantia gelatinosa neurons of the subnucleus caudalis in mice.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2021.2016746
Abstract: Although a number of studies have reported that resveratrol has analgesic effects, the direct effect of resveratrol on substantia gelatinosa (SG) neurons of the trigeminal subnucleus caudalis (Vc) involved in orofacial nociceptive transmission has not… read more here.
Keywords: inward currents; glycine receptors; gelatinosa neurons; substantia gelatinosa ... See more keywords
Estimates of persistent inward currents in lower limb motoneurons are larger in females than males.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurophysiology"
DOI: 10.1152/jn.00043.2023
Abstract: Non-invasive recordings of motor unit (MU) spike trains help us understand how the nervous system controls movement and how it adapts to various physiological conditions. The majority of participants in human and non-human animal physiology… read more here.
Keywords: persistent inward; estimates persistent; physiology; sex ... See more keywords
ESTIMATES OF PERSISTENT INWARD CURRENTS INCREASE WITH THE LEVEL OF VOLUNTARY DRIVE IN LOW-THRESHOLD MOTOR UNITS OF PLANTAR FLEXOR MUSCLES.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of neurophysiology"
DOI: 10.1152/jn.00697.2020
Abstract: This study tested if estimates of persistent inward currents (PICs) in the plantar flexors would increase with the level of voluntary drive. High-density surface electromyograms were collected from soleus and gastrocnemius medialis of 21 participants… read more here.
Keywords: estimates persistent; drive; voluntary drive; persistent inward ... See more keywords
The Interaction Between Na+ and Ca2+ Inward Currents in Cardiac Propagation.
Sign Up to like & getrecommendations! Published in 2020 at "Circulation Research"
DOI: 10.1161/circresaha.120.318316
Abstract: The discovery of a slow Ca 2+ inward current in the heart by Reuter in 19671 was a milestone in the understanding of cardiac electrical activity. This current was shown to be the missing link… read more here.
Keywords: interaction ca2; propagation; inward currents; currents cardiac ... See more keywords