Articles with "inwardly rectifying" as a keyword



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Inwardly Rectifying K+ Currents in Cultured Oligodendrocytes from Rat Optic Nerve are Insensitive to pH

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Published in 2017 at "Neurochemical Research"

DOI: 10.1007/s11064-017-2242-8

Abstract: Inwardly rectifying K+ (Kir) channel expression signals at an advanced stage of maturation during oligodendroglial differentiation. Knocking down their expression halts the generation of myelin and produces severe abnormalities in the central nervous system. Kir4.1… read more here.

Keywords: kir; kir channels; currents cultured; rectifying currents ... See more keywords

Inhibition of 17-beta-estradiol on neuronal excitability via enhancing GIRK1-mediated inwardly rectifying potassium currents and GIRK1 expression

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Published in 2017 at "Journal of the Neurological Sciences"

DOI: 10.1016/j.jns.2017.02.034

Abstract: BACKGROUND Catamenial epilepsy is a common central nervous system disease in female, which is influenced by the 17-β-estradiol (estrogen) level during the menstrual cycle. Low level ( read more here.

Keywords: potassium; estrogen; level; inwardly rectifying ... See more keywords
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Permissive role of reduced inwardly-rectifying potassium current density in the automaticity of the guinea pig pulmonary vein myocardium.

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Published in 2017 at "Journal of pharmacological sciences"

DOI: 10.1016/j.jphs.2016.12.006

Abstract: The electrophysiological properties underlying the automaticity of the guinea pig pulmonary vein myocardium were studied. About 30% of the isolated pulmonary vein tissue preparations showed spontaneous electrical activity, as shown by glass microelectrode recordings from… read more here.

Keywords: vein; potassium current; density; pulmonary vein ... See more keywords
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Non‐sedating antihistamines block G‐protein‐gated inwardly rectifying K+ channels

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Published in 2019 at "British Journal of Pharmacology"

DOI: 10.1111/bph.14717

Abstract: A second‐generation antihistamine, terfenadine, is known to induce arrhythmia by blocking hERG channels. In this study, we have shown that terfenadine also inhibits the activity of G‐protein‐gated inwardly rectifying K+ (GIRK) channels, which regulate the… read more here.

Keywords: protein gated; sedating antihistamines; gated inwardly; inwardly rectifying ... See more keywords