Palladium-catalyzed meta-C H bond iodination of arenes with I2
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2019.09.057
Abstract: Abstract Palladium-catalyzed highly meta-selective C H iodination of phenylacetic acid, benzylphosphonate and benzylsulfonate scaffolds with molecular I2 is developed using a pyridine-type template. The practical ester linkages enable the directing template easily installed and readily… read more here.
Keywords: iodination; meta bond; palladium catalyzed; catalyzed meta ... See more keywords
Abiotic formation of organoiodine compounds by manganese dioxide induced iodination of dissolved organic matter.
Sign Up to like & getrecommendations! Published in 2018 at "Environmental pollution"
DOI: 10.1016/j.envpol.2018.02.001
Abstract: Iodination of dissolved organic matter (DOM) initiated by manganese oxide may represent an important source of organoiodine compounds (OICs) for iodide-containing waters. Here, Suwannee River natural organic matter was selected as model DOM, the OICs… read more here.
Keywords: iodination; iodination dissolved; formation; organic matter ... See more keywords
Iodination of terminal alkynes using KI/CuSO4 – A facile method with potential for radio-iodination
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.02.041
Abstract: Graphical abstract Herein, we report an efficient new method for iodination of terminal alkynes using stoichiometric KI and CuSO4 in acetate buffer that holds promise for further development into a method for radio-iodination. read more here.
Keywords: iodination; iodination terminal; terminal alkynes; method ... See more keywords
Selective C–H Iodination of (Hetero)arenes
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DOI: 10.1021/acs.orglett.1c01530
Abstract: Iodoarenes are versatile intermediates and common synthetic targets in organic synthesis. Here, we present a strategy for selective C–H iodination of (hetero)arenes with a broad functional group tolerance. We demonstrate the utility and differentiation to… read more here.
Keywords: iodination; iodination hetero; hetero arenes; selective iodination ... See more keywords
Native Amino Group Directed Site-Selective ε-C(sp2)-H Iodination of Primary Amines.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04288
Abstract: Selective remote C-H activating amines using unmodified NH2 as a native directing group demonstrate compelling synthetic utilities. The 3-arylpropan-1-amine moiety is present in many drugs and candidates in clinical trials. Selective iodination of 3-arylpropan-1-amines on… read more here.
Keywords: native amino; sp2 iodination; selective sp2; group ... See more keywords
In Situ Generation of Chiroptically-Active Gold-Peptide Superstructures Promoted by Iodination
Sign Up to like & getrecommendations! Published in 2019 at "ACS Nano"
DOI: 10.1021/acsnano.8b08805
Abstract: Peptide-mediated routes to the synthesis of plasmonic nanoparticles have been drawing increasing attention for the development of chiroptically active nanoscale architectures. However, designing a multifunctional peptide able to drive the formation of structurally defined nanomaterials… read more here.
Keywords: iodination; peptide; active gold; situ generation ... See more keywords
(E)-Di-iodination of Alkynes Using Dried Dowex H+/NaI Approach
Sign Up to like & getrecommendations! Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.9b02577
Abstract: We investigated the usefulness of the dried Dowex H+/NaI approach for the selective di-iodination of alkynes. The Dowex H+/NaI approach selectively produces only (E)-di-iodinated products; it is very straightforward and nontoxic. The utilization of 2-propanol… read more here.
Keywords: iodination; dowex nai; dried dowex; approach ... See more keywords
Facile C–H iodination of electron deficient benzodithiophene-S,S-tetraoxide for the development of n-type polymers
Sign Up to like & getrecommendations! Published in 2020 at "Polymer Chemistry"
DOI: 10.1039/d0py01292k
Abstract: A C–H iodination reaction of the electron-poor building block, benzo[1,2-b:4,5-b0]-dithiophene-1,1,5,5-tetraoxide has been reported. This facile functionalization has led to the development of two novel n-type donor–acceptor conjugated polymers. read more here.
Keywords: iodination; iodination electron; facile iodination; type ... See more keywords
Sterically controlled isodesmic late-stage C–H iodination of arenes
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Science"
DOI: 10.1039/d3sc00801k
Abstract: Aryl iodides are key motifs in organic chemistry due to their versatility as linchpins in metal-mediated cross-coupling reactions for synthesis and drug discovery. These scaffolds are typically prepared indirectly from prefunctionalized starting materials or via… read more here.
Keywords: iodination arenes; sterically controlled; late stage; iodination ... See more keywords
C(sp2)–H Iodination by a Rhodium(III) Complex Supported by a Redox-active Ligand Bearing Amidophenolato Moieties
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DOI: 10.1246/cl.200178
Abstract: C(sp2)–H iodination of m-xylene promoted by a rhodium(III) complex supported by a redox-active ligand, (nBu4N)[RhIIIL3−(MeCN)Cl] (1Cl), is reported. The iodination reaction involves an electrophili... read more here.
Keywords: iodination; supported redox; complex supported; sp2 iodination ... See more keywords
A Green Chemical Approach for Iodination of Pyrimidine Derivatives by Mechanical Grinding under Solvent-Free Conditions
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27196386
Abstract: The iodination of pyrimidines is usually carried out by using toxic reagents under acidic conditions, such as with sulfuric acid and nitric acid. To avoid toxic reagents, we developed a simple and eco-friendly approach for… read more here.
Keywords: approach iodination; solvent free; iodination pyrimidine; pyrimidine derivatives ... See more keywords