Three‐Component Synthesis of Fluorescent 1,4‐Benzothiazin‐2‐ones through Thiol‐Free Iodine‐Catalyzed Cyclization
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202400715
Abstract: A convergent synthesis of 2H‐benzo[b][1,4]thiazin‐2‐one was achieved via iodine‐catalyzed three‐component reaction. This strategy involves the formation of two new C–S bonds and a C–N bond from the readily available precursors ‐ aryl methyl ketones, p‐anisidine, and… read more here.
Keywords: three component; iodine catalyzed; synthesis fluorescent; component synthesis ... See more keywords
Iodine-catalyzed amination of benzothiazoles with KSeCN in water to access primary 2-aminobenzothiazoles
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2021.08.070
Abstract: Abstract A facile and sustainable approach for the amination of benzothiazoles with KSeCN using iodine as the catalyst in water has been disclosed under transition-metal free conditions. The reaction proceeded smoothly to afford various primary… read more here.
Keywords: benzothiazoles ksecn; primary aminobenzothiazoles; iodine catalyzed; amination benzothiazoles ... See more keywords
Novel Hypervalent Iodine Catalyzed Synthesis of α-Sulfonoxy Ketones: Biological Activity and Molecular Docking Studies
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.130492
Abstract: Abstract The novel di((camphorsulfonyl)oxy)iodo]benzene (DCIB) was synthesized from [Bis(trifluoroacetoxy)iodo]benzene in the mild conditions. The α-sulfonoxylation of various ketones with novel hypervalent iodine was reported in excellent yield. α-Hydroxyketones were synthesized from α-sulfonoxy compounds (caphorsulfonoxy ketones)… read more here.
Keywords: sulfonoxy ketones; hypervalent iodine; novel hypervalent; inhibition ... See more keywords
Metal- and solvent-free, iodine-catalyzed cyclocondensation and CH bond sulphenylation: A facile access to C-4 sulfenylated pyrazoles via a domino multicomponent reaction
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.02.046
Abstract: Abstract We describe herein a green and efficient MCRs protocol to synthesize C-4 sulfenylated pyrazoles by iodine-catalyzed cyclocondensation and direct C H bond sulphenylation reactions. Through this protocol, two new C N bonds and one… read more here.
Keywords: iodine catalyzed; bond sulphenylation; bond; metal solvent ... See more keywords
Study on the iodine-catalyzed reaction of 3-aminopyrazine-2-carbohydrazide and 2-(arylethynyl)benzaldehydes
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron"
DOI: 10.1016/j.tet.2018.02.007
Abstract: Abstract At 60 °C in DMSO, the iodine-catalyzed reaction of 3-aminopyrazine-2-carbohydrazide and 2-(arylethynyl)benzaldehydes led hydrazones. Increasing the reaction temperature to 100 °C, the amino and amido still indicated inactive, only the imine took part in the addition… read more here.
Keywords: iodine catalyzed; aminopyrazine carbohydrazide; reaction aminopyrazine; carbohydrazide arylethynyl ... See more keywords
Iodine-Catalyzed Borylation of Benzylic Alcohols.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00367
Abstract: Direct borylation of benzylic alcohols has been achieved via an iodine-catalyzed process. This transition-metal-free borylation transformation is compatible with various functional groups and provides a practical and convenient method to access important and useful benzylic… read more here.
Keywords: catalyzed borylation; borylation; benzylic alcohols; borylation benzylic ... See more keywords
Molecular Iodine-Catalyzed Synthesis of Imidazo[1,2-a]Pyridines: Screening of Their In Silico Selectivity, Binding Affinity to Biological Targets, and Density Functional Theory Studies Insight
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01570
Abstract: The present paper discloses an ultrasonication strategy assisted by molecular iodine as an environmentally benign catalyst leading to the synthesis of pharmacologically significant imidazo[1,2-a]pyridine scaffolds. The molecular-iodine-catalyzed approach for the synthesis of biologically active synthetic… read more here.
Keywords: theory; synthesis; iodine; molecular iodine ... See more keywords
Iodine-Catalyzed Functionalization of Primary Aliphatic Amines to Oxazoles, 1,4-Oxazines, and Oxazinones
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DOI: 10.1021/acsomega.9b03501
Abstract: Unprecedented I2-catalyzed α,α-C(sp3)-H, decarboxylative α-C(sp3)-H, lactonized α-C(sp3)-H, and α,β-C(sp3)-H functionalized 5- and 6-annulation as well as α-C(sp3)-H activated 6-lactonization of primary aliphatic amines are devised under aerobic conditions. The metal-free sustainable strategy was employed for… read more here.
Keywords: iodine catalyzed; primary aliphatic; oxazoles oxazines; catalyzed functionalization ... See more keywords
Iodine-catalyzed convergent aerobic dehydro-aromatization toward benzazoles and benzazines
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DOI: 10.1039/c9ra10964a
Abstract: An iodine-catalyzed aerobic dehydro-aromatization has been developed, providing straightforward and efficient access to various benzoazoles and benzoazines. The present transition-metal-free protocol enables the dehydro-aromatization of tetrahydrobenzazoles and tetrahydroquinolines with molecular oxygen as the green oxidant,… read more here.
Keywords: dehydro aromatization; iodine catalyzed; aerobic dehydro; aromatization ... See more keywords
Iodine-catalyzed α,β-dehydrogenation of ketones and aldehydes generating conjugated enones and enals
Sign Up to like & getrecommendations! Published in 2020 at "New Journal of Chemistry"
DOI: 10.1039/d0nj01244k
Abstract: A transition metal-free α,β-dehydrogenation of ketones and aldehydes was developed. This reaction was conducted in a facile I2/KI/DMSO system to produce the corresponding unsaturated compounds in good to high yields. The gram-scale experiment also indicated… read more here.
Keywords: iodine catalyzed; ketones aldehydes; dehydrogenation ketones; aldehydes generating ... See more keywords
Molecular iodine-catalyzed multicomponent synthesis of α-cyanopyrrolines with ambient air as the oxidant under neat conditions
Sign Up to like & getrecommendations! Published in 2020 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo01113d
Abstract: In this work, a variety of α-cyanopyrrolines were efficiently synthesized from alkenes, TMSCN and N,N-disubstituted formamides via molecular iodine-catalyzed tandem reaction under neat and mild conditions. This method applies ambient air as the sole oxidant… read more here.
Keywords: ambient air; iodine catalyzed; molecular iodine; catalyzed multicomponent ... See more keywords