Methyl-2,2-difluoro-2-(fluorosulfonyl) acetate (MDFA)/copper (I) iodide mediated and tetrabutylammonium iodide promoted trifluoromethylation of 1-aryl-4-iodo-1,2,3-triazoles
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2020.109516
Abstract: Abstract While several methods are available for the synthesis of a host of trifluoromethylated heterocycles, very few of them have been applied to access 4-trifluoromethylated 1,2,3-triazoles. We report herein a general methodology for the trifluoromethylation… read more here.
Keywords: aryl iodo; tetrabutylammonium iodide; difluoro fluorosulfonyl; trifluoromethylation aryl ... See more keywords
Facile synthesis of bromo- and iodo-1,2,3-triazoles
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.07.016
Abstract: Abstract Facile synthetic routes to bromo- and iodo-1,2,3-triazoles were achieved. Diiodo-1,2,3-triazole was directly obtained from 1,2,3-triazole, and dihalo-1,2,3-triazoles were converted to halo-1,2,3-triazoles in good yields without protection by NH. Unsymmetrical 4-bromo-5-iodo-1,2,3-triazole was synthesized from bromo-1,2,3-triazole.… read more here.
Keywords: facile synthesis; iodo triazoles; bromo; bromo iodo ... See more keywords