Enantioselective Friedel-Crafts Alkylation of Furans with o-Quinone Methide Using a Chiral Oxazaborolidinium Ion Catalyst.
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DOI: 10.1021/acs.orglett.2c00404
Abstract: A chiral Lewis acid-catalyzed enantioselective Friedel-Crafts furan alkylation with in situ-generated o-quinone methides has been developed. In the presence of a chiral oxazaborolidinium ion catalyst, the reaction proceeded in high yield (up to 99%) with… read more here.
Keywords: oxazaborolidinium ion; ion catalyst; chiral oxazaborolidinium; alkylation ... See more keywords