Usnea Acid-Incorporated Ca2+ /Mn2+ Ions Reservoirs for Elevated Ion-Interference Therapy through Synergetic Biocatalysis and Osmolarity Imbalance.
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DOI: 10.1002/smll.202300370
Abstract: Ion-interference therapy (IIT) utilizes ions to disturb intracellular biological processes and has been received increasing attention in tumor treatments recently. However, the low therapeutic efficiency still hinders its further biological applications. Herein, via a simple… read more here.
Keywords: ca2 mn2; interference therapy; ion interference; mn2 ions ... See more keywords
Tumor Microenvironment-Responsive Yolk-Shell NaCl@Virus-Inspired Tetrasulfide-Organosilica for Ion-Interference Therapy via Osmolarity Surge and Oxidative Stress Amplification.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c09496
Abstract: Ion-interference therapy, which utilizes ions to disturb intracellular biological processes, provides inspiration for tumor therapy. Artificially reversing osmotic pressure by transporting large amounts of physiological ions to tumor cells is a straightforward yet low-toxic strategy… read more here.
Keywords: ssss vhms; interference therapy; ion interference; tumor ... See more keywords
Growth of ZIF-8 Nanoparticles In Situ on Graphene Oxide Nanosheets: A Multifunctional Nanoplatform for Combined Ion-Interference and Photothermal Therapy.
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DOI: 10.1021/acsnano.2c05532
Abstract: The regulation of intracellular ions' overload to interrupt normal bioprocesses and cause cell death has been developed as an efficient strategy (named as ion-interference therapy/IIT) to treat cancer. In this study, we design a multifunctional… read more here.
Keywords: multifunctional nanoplatform; ion interference; therapy;
Dual-infinite coordination polymer-engineered nanomedicines for dual-ion interference-mediated oxidative stress-dependent tumor suppression.
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DOI: 10.1039/d3mh00001j
Abstract: Recently, nanomedicine design has shifted from simple nanocarriers to nanodrugs with intrinsic antineoplastic activities for therapeutic performance optimization. In this regard, degradable nanomedicines containing functional inorganic ions have blazed a highly efficient and relatively safe… read more here.
Keywords: infinite coordination; icps; oxidative stress; ion interference ... See more keywords
Ion Interference Therapy of Tumors Based on Inorganic Nanoparticles
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DOI: 10.3390/bios12020100
Abstract: As an essential substance for cell life activities, ions play an important role in controlling cell osmotic pressure balance, intracellular acid–base balance, signal transmission, biocatalysis and so on. The imbalance of ion homeostasis in cells… read more here.
Keywords: inorganic nanoparticles; ion; ion interference; interference therapy ... See more keywords