New urea-modified paper substrate for enhanced analytical performance of negative ion mode paper spray mass spectrometry.
Sign Up to like & getrecommendations! Published in 2017 at "Talanta"
DOI: 10.1016/j.talanta.2017.01.076
Abstract: Electrospray ionization mass spectrometry (ESI-MS) analysis in the negative ion mode is adversely affected by ionization suppression caused by electrical discharge and the presence of salts. Paper spray mass spectrometry (PS-MS) also suffers from the… read more here.
Keywords: paper substrate; mass spectrometry; ion mode; paper ... See more keywords
Utility of Ion-Mobility Spectrometry for Deducing Branching of Multiply Charged Glycans and Glycopeptides in a High-Throughput Positive ion LC-FLR-IMS-MS Workflow.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c01954
Abstract: High-throughput glycan analysis has become an important part of biopharmaceutical production and quality control. However, it is still a significant challenge in the field of glycomics to easily deduce isomeric glycan structures, especially in a… read more here.
Keywords: ion mode; flr; ion; positive ion ... See more keywords
Dual fragmentation via collision-induced and oxygen attachment dissociations using water and its radicals for C=C position-resolved lipidomics
Sign Up to like & getrecommendations! Published in 2025 at "Communications Chemistry"
DOI: 10.1038/s42004-025-01525-y
Abstract: Oxygen attachment dissociation (OAD) is a tandem mass spectrometry (MS/MS) technique for annotating the positions of double bonds (C=C) in complex lipids. Although OAD has been used for untargeted lipidomics, its availability has been limited… read more here.
Keywords: oad; ion mode; fragmentation; oxygen attachment ... See more keywords
Dependence of matrix effect on ionization polarity during LC–ESI–MS analysis of derivatized amino acids in some natural samples
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Mass Spectrometry"
DOI: 10.1177/1469066717711026
Abstract: Matrix effect, the influence of co-eluting components on the ionization efficiency of the analyte, affects the trueness and precision of the LC–ESI–MS analysis. Derivatization can reduce or eliminate matrix effect, for example, diethyl ethoxymethylenemalonate (DEEMM)… read more here.
Keywords: matrix effect; amino acids; effect; ion mode ... See more keywords
Untargeted metabolomics of saliva in caries-active and caries-free children in the mixed dentition
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1104295
Abstract: Objective To compare the differences in salivary metabolites between caries-active and caries-free children in the mixed dentition, and explore their correlation with caries status. Methods The study involved 20 children (aged 8–9 years) in the… read more here.
Keywords: free children; caries free; ion mode; caries active ... See more keywords
Untargeted metabolomics reveals the metabolic characteristics and biomarkers of obstetric antiphospholipid syndrome and undifferentiated connective tissue disease
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2025.1632244
Abstract: Background The clinical differentiation between obstetric antiphospholipid syndrome (OAPS) and undifferentiated connective tissue disease (UCTD) presents significant diagnostic challenges. This study employs metabolomics to investigate metabolic reprogramming patterns in OAPS and UCTD, aiming to identify… read more here.
Keywords: ion mode; mode metabolites; ion; metabolites upregulated ... See more keywords